(R)-2-amino-2-(4-bromophenyl)ethanol

Base Information

Chemical Name:(R)-2-amino-2-(4-bromophenyl)ethanol
CAS No.:354153-64-3
Molecular Formula:C8H10BrNO
Molecular Weight:216.077
Hs Code.:2922190090
DSSTox Substance ID:DTXSID901295801
Nikkaji Number:J1.544.984E
Mol file:354153-64-3.mol

Synonyms:(R)-2-amino-2-(4-bromophenyl)ethanol;354153-64-3;(2R)-2-amino-2-(4-bromophenyl)ethan-1-ol;(2R)-2-amino-2-(4-bromophenyl)ethanol;(R)-b-Amino-4-bromo-benzeneethanol;MFCD09256373;SCHEMBL1553953;KTNHFPRYCCCOQV-QMMMGPOBSA-N;DTXSID901295801;AKOS015928767;(R)-beta-Amino-4-bromo-benzeneethanol;AM10068;(betaR)-beta-Amino-4-bromobenzeneethanol;DS-10290;(R)-2-Amino-2-(4-bromo-phenyl)-ethanol;(R)-2-Amino-2-(4-bromophenyl)ethan-1-ol;CS-0131603;D83092;EN300-370981;A912308

Suppliers and Price of (R)-2-amino-2-(4-bromophenyl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-2-Amino-2-(4-bromophenyl)ethanol 95+%
1g
$ 251.00

Chemenu
(R)-2-Amino-2-(4-bromophenyl)ethanol 95%
5g
$ 1257.00

Chemenu
(R)-2-Amino-2-(4-bromophenyl)ethanol 95%
1g
$ 393.00

American Custom Chemicals Corporation
(2R)-2-AMINO-2-(4-BROMOPHENYL)ETHAN-1-OL 95.00%
5MG
$ 496.18

Ambeed
(R)-2-Amino-2-(4-bromophenyl)ethanol 95%
1g
$ 290.00

Ambeed
(R)-2-Amino-2-(4-bromophenyl)ethanol 95%
250mg
$ 99.00

Ambeed
(R)-2-Amino-2-(4-bromophenyl)ethanol 95%
100mg
$ 63.00

Alichem
(R)-2-Amino-2-(4-bromophenyl)ethanol
5g
$ 1065.11

Alichem
(R)-2-Amino-2-(4-bromophenyl)ethanol
1g
$ 332.82

AK Scientific
(R)-2-Amino-2-(4-bromophenyl)ethanol
250mg
$ 201.00

Total 8 raw suppliers

Chemical Property of (R)-2-amino-2-(4-bromophenyl)ethanol

Chemical Property:

Boiling Point:341.6±27.0 °C(Predicted)
PKA:12.43±0.10(Predicted)
PSA：46.25000
Density:1.539±0.06 g/cm3(Predicted)
LogP:2.14150
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:214.99458
Heavy Atom Count:11
Complexity:113

Purity/Quality:

97% ^*data from raw suppliers

(R)-2-Amino-2-(4-bromophenyl)ethanol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(CO)N)Br
Isomeric SMILES:C1=CC(=CC=C1[C@H](CO)N)Br

Technology Process of (R)-2-amino-2-(4-bromophenyl)ethanol

There total 10 articles about (R)-2-amino-2-(4-bromophenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 849178-85-4,1379546-68-5
tert-butyl N-[(1R)-1-(4-bromophenyl)-2-hydroxy-ethyl]carbamate

: 354153-64-3
(R)-2-amino-2-(4-bromophenyl)ethan-1-ol

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; methanol; for 1.5h;

Reference yield: 90.0%

: (R)-2-azido-2-(4-bromophenyl)ethan-1-ol

: 354153-64-3
(R)-2-amino-2-(4-bromophenyl)ethan-1-ol

Guidance literature:: With water; triphenylphosphine; In tetrahydrofuran; at 70 ℃;
DOI:10.1016/j.tetasy.2015.12.002

Reference yield:

: 2039-82-9
1-bromo-4-ethenyl-benzene

: 354153-64-3
(R)-2-amino-2-(4-bromophenyl)ethan-1-ol

Guidance literature:: Multi-step reaction with 5 steps

1: 68 percent / K₂OsO₂(OH)4; DABCO; K₂CO₃ / K₃Fe(CN)6 / 2-methyl-propan-2-ol; H₂O / 0 °C

2: 83 percent / CH₃CN; trifluoromethanesulfonic acid / -40 - 25 °C

3: 61 percent / pyridine / CH₂Cl₂ / 18.5 h / 0 °C

4: NaOH / methanol / 20 °C

5: 98percent H₂SO₄ / H₂O / Heating

With pyridine; 1,4-diaza-bicyclo[2.2.2]octane; sodium hydroxide; potassium dioxotetrahydroxoosmate(VI); trifluorormethanesulfonic acid; potassium carbonate; acetonitrile; potassium hexacyanoferrate(III); In methanol; dichloromethane; water; tert-butyl alcohol; 2: Ritter rearrangement;
DOI:10.1002/1099-0690(200105)2001:10<1937::aid-ejoc1937>3.3.co;2-u