(6-phenylimidazo[1,2-b]pyridazin-3-yl)methanol

Base Information

• Chemical Name: (6-phenylimidazo[1,2-b]pyridazin-3-yl)methanol
• CAS No.: 1002309-36-5
• Molecular Formula: C₁₃H₁₁N₃O
• Molecular Weight: 225.25
• Mol file: 1002309-36-5.mol

Synonyms:(6-phenylimidazo[1,2-b]pyridazin-3-yl)methanol

Chemical Property of (6-phenylimidazo[1,2-b]pyridazin-3-yl)methanol

Chemical Property:

Purity/Quality:

95+% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (6-phenylimidazo[1,2-b]pyridazin-3-yl)methanol

There total 1 articles about (6-phenylimidazo[1,2-b]pyridazin-3-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(6-chloroimidazo[1,2-b]pyridazin-3-yl)methanol (675580-49-1) + phenylboronic acid (98-80-6) → (6-phenylimidazo[1,2-b]pyridazin-3-yl)methanol (1002309-36-5)

Guidance literature:

With sodium hydrogencarbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; water; at 80 ℃; for 1h;

Reference yield:

4-chloro-7-methoxyquinoline (68500-37-8) + (6-phenylimidazo[1,2-b]pyridazin-3-yl)methanol (1002309-36-5) → 7-methoxy-4-((6-phenylimidazo[1,2-b]pyridazin-3-yl)methoxy)quinoline

Guidance literature:

With caesium carbonate; In dimethyl sulfoxide; at 120 - 130 ℃; for 34.0833h; Microwave irradiation;

upstream raw materials:

(6-chloroimidazo[1,2-b]pyridazin-3-yl)methanol

phenylboronic acid

Refernces