Methyl 3-Chloro-4-Iodobenzoate

Base Information

• Chemical Name: Methyl 3-Chloro-4-Iodobenzoate
• CAS No.: 874569-39-8
• Molecular Formula: C8H6ClIO2
• Molecular Weight: 296.49
• Hs Code.: 2916399090
• Mol file: 874569-39-8.mol

Synonyms:1-Piperidinecarboxylic acid,4-iodo-,methyl ester;methyl 4-iodo-1-piperidinecarboxylate;methyl 4-iodo-3-chlorobenzoate;

Chemical Property of Methyl 3-Chloro-4-Iodobenzoate

Chemical Property:

• PSA: 26.30000
• LogP: 2.73120

Purity/Quality:

99%+ ^*data from raw suppliers

Methyl3-Chloro-4-iodobenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 3-Chloro-4-Iodobenzoate

There total 1 articles about Methyl 3-Chloro-4-Iodobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-amino-3-chlorobenzoate (84228-44-4) → methyl 3-chloro-4-iodobenzoate (874569-39-8)

Guidance literature:

With n-Amyl nitrite; iodine; for 1h; Heating / reflux;

Reference yield:

methyl 3-chloro-4-iodobenzoate (874569-39-8) + 8-{[tert-butyl(dimethyl)silyl]oxy}-2-azaspiro[4.5]decan-1-one → methyl 4-[8-{[tert-butyl(dimethyl)silyl]oxy}-1-oxo-2-azaspiro[4.5]dec-2-yl]-3-chlorobenzoate

Guidance literature:

With potassium phosphate; copper(l) iodide; N,N`-dimethylethylenediamine; In o-xylene; at 140 ℃; for 24h; Inert atmosphere; Microwave irradiation;

Reference yield:

methyl 3-chloro-4-iodobenzoate (874569-39-8) → methyl 2''-({(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl}methyl)-2-chloro-4'-methoxy-4''-(trifluoromethyl)-1,1':3',1''-terphenyl-4-carboxylate + methyl 2''-({(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl}methyl)-2-chloro-4'-methoxy-4''-(trifluoromethyl)-1,1':3',1''-terphenyl-4-carboxylate

Guidance literature:

Multi-step reaction with 3 steps

1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / ethanol; water; toluene / Heating / reflux

2: iodine; silver sulfate / methanol; ethyl acetate / 6 h / 20 °C

3: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / ethanol; water; toluene / 2 h / Heating / reflux

With iodine; sodium carbonate; silver sulfate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In methanol; ethanol; water; ethyl acetate; toluene;

upstream raw materials:

methyl 4-amino-3-chlorobenzoate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 874569-39-8 Methyl 3-Chloro-4-Iodobenzoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send