6,7-epoxycanrenone

Base Information

• Chemical Name: 6,7-epoxycanrenone
• CAS No.: 114577-01-4
• Molecular Formula: C₂₂H₂₈O₄
• Molecular Weight: 356.462
• Mol file: 114577-01-4.mol

Synonyms:Spiro[6,7-epoxy-17H-cyclopenta[a]phenanthrene-17,2'(5'H)-furan],pregn-4-ene-21-carboxylic acid deriv.; 6a,7a-Epoxycanrenone

Chemical Property of 6,7-epoxycanrenone

Chemical Property:

• Vapor Pressure: 2.95E-12mmHg at 25°C
• Boiling Point: 552.6°Cat760mmHg
• Flash Point: 242.8°C
• PSA: 55.90000
• Density: 1.26g/cm³
• LogP: 3.58130

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6,7-epoxycanrenone

There total 2 articles about 6,7-epoxycanrenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

canrenone (976-71-6) → 6α,7α-Epoxycanrenone (114577-01-4)

Guidance literature:

With 2,6-di-tert-butyl-4-methyl-phenol; 3-chloro-benzenecarboperoxoic acid; In chloroform; for 1.66667h; Heating;

DOI:10.1016/0039-128X(89)90078-0

Reference yield:

canrenone (976-71-6) → C22H27ClO3 (66175-65-3) + 6β,7β-Epoxy-17β-hydroxy-3-oxo-4,6-pregnadien-21-carbonsaeure-γ-lacton (110078-66-5,114577-01-4)

Guidance literature:

With formic acid; tert-hypochlorite; potassium carbonate; Yield given. Multistep reaction; 1.) 1 h, RT 2.) CH₃OH, H₂O, 80 deg C, 15 min;

upstream raw materials:

canrenone