H-D-THR(TBU)-OH

Base Information

• Chemical Name: H-D-THR(TBU)-OH
• CAS No.: 119323-52-3
• Molecular Formula: C8H17NO3
• Molecular Weight: 175.228
• Mol file: 119323-52-3.mol

Synonyms:O-T-BUTYL-D-THREONINE;H-D-THR(TBU)-OH;H-D-ALLO-THR(TBU)-OH;D-THREONINE(TBU)-OH;D-Thr(tBu)-OH;(2R,3R)-2-Amino-3-(tert-butoxy)butanoic acid

Chemical Property of H-D-THR(TBU)-OH

Chemical Property:

• Boiling Point: 275.3±30.0 °C(Predicted)
• PKA: 2.14±0.10(Predicted)
• PSA: 72.55000
• Density: 1.055±0.06 g/cm3(Predicted)
• LogP: 1.30220
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

H-D-Allo-thr(tbu)-oh ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H-D-THR(TBU)-OH

There total 3 articles about H-D-THR(TBU)-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(O-tert-butyl)-L-threonine (4378-13-6,201353-89-1) → (2R,3R)-2-Amino-3-tert-butoxy-butyric acid (119323-52-3,201353-89-1)

Guidance literature:

In water; at 140 ℃; Rate constant; pH 8.0;

DOI:10.1021/jo00280a017

Reference yield:

→ H-Thr(t-Bu)-OH (4378-13-6,119323-52-3,201353-89-1)

Guidance literature:

aus 1c;

Reference yield:

C9H19NO3 (1227750-69-7) → (2R,3R)-2-Amino-3-tert-butoxy-butyric acid (119323-52-3,201353-89-1)

Guidance literature:

With water; sodium hydroxide; at 0 ℃;

DOI:10.1038/nchem.554

upstream raw materials:

(O-tert-butyl)-L-threonine

C₉H₁₉NO₃

Downstream raw materials:

N^α-(9-Fluorenylmethoxycarbonyl)-D-allothreonine t-butyl ether