5-cyclobutyl-1,3,4-oxadiazol-2-amine

Base Information

• Chemical Name: 5-cyclobutyl-1,3,4-oxadiazol-2-amine
• CAS No.: 89464-84-6
• Molecular Formula: C₆H₉N₃O
• Molecular Weight: 139.157
• Hs Code.: 2934999090
• Mol file: 89464-84-6.mol

Synonyms:5-cyclobutyl-1,3,4-oxadiazol-2-amine;5-cyclobutyl-1,3,4-oxadiazol-2-amine(SALTDATA: FREE);(5-cyclobutyl-1,3,4-oxadiazol-2-yl)amine

Chemical Property of 5-cyclobutyl-1,3,4-oxadiazol-2-amine

Chemical Property:

• Vapor Pressure: 0.00201mmHg at 25°C
• Boiling Point: 290.9°C at 760 mmHg
• Flash Point: 129.7°C
• PSA: 64.94000
• Density: 1.304g/cm³
• LogP: 1.50050

Purity/Quality:

97% ^*data from raw suppliers

5-Cyclobutyl-1,3,4-oxadiazol-2-amine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-cyclobutyl-1,3,4-oxadiazol-2-amine

There total 1 articles about 5-cyclobutyl-1,3,4-oxadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromocyane (506-68-3) + cyclobutanecarboxylic acid hydrazide (98069-56-8) → 5-cyclobutyl-1,3,4-oxadiazol-2-amine (89464-84-6)

Guidance literature:

In methanol;

Reference yield:

5-cyclobutyl-1,3,4-oxadiazol-2-amine (89464-84-6) → C26H30N4O3

Guidance literature:

Multi-step reaction with 2 steps

1: copper(ll) bromide; tert.-butylnitrite / acetonitrile / 5 h / 0 - 20 °C

2: N,N-dimethyl acetamide / 0.75 h / 120 °C / Microwave irradiation

With tert.-butylnitrite; copper(ll) bromide; In N,N-dimethyl acetamide; acetonitrile;

DOI:10.1021/acsmedchemlett.9b00117

Reference yield:

5-cyclobutyl-1,3,4-oxadiazol-2-amine (89464-84-6) → 2-((1r,4r)-4-(4-(5-(5-cyclobutyl-1,3,4-oxadiazol-2-ylamino)pyridin-2-yl)phenyl)cyclohexyl)acetic acid

Guidance literature:

Multi-step reaction with 3 steps

1: copper(ll) bromide; tert.-butylnitrite / acetonitrile / 5 h / 0 - 20 °C

2: N,N-dimethyl acetamide / 0.75 h / 120 °C / Microwave irradiation

3: sodium hydroxide; water / acetonitrile / 2 h / 20 °C

With tert.-butylnitrite; water; sodium hydroxide; copper(ll) bromide; In N,N-dimethyl acetamide; acetonitrile;

DOI:10.1021/acsmedchemlett.9b00117

upstream raw materials:

bromocyane

cyclobutanecarboxylic acid hydrazide

Downstream raw materials:

4-chloro-N-(5-cyclobutyl-[1,3,4]oxadiazol-2-yl)-benzenesulfonamide

N-(5-cyclobutyl-[1,3,4]oxadiazol-2-yl)-benzenesulfonamide

N-(5-cyclobutyl-[1,3,4]oxadiazol-2-yl)-toluene-4-sulfonamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 89464-84-6 5-cyclobutyl-1,3,4-oxadiazol-2-amine

Send

Send

Metric Ton KG G Pound L ML

Send

Send