N-[2-(1H-indol-3-yl)ethyl]-N-(4-methylphenyl)formamide

Base Information

Chemical Name:N-[2-(1H-indol-3-yl)ethyl]-N-(4-methylphenyl)formamide
CAS No.:881597-49-5
Molecular Formula:C18H18N2O
Molecular Weight:278.354
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30696713
Wikidata:Q82626406
Mol file:881597-49-5.mol

Synonyms:DTXSID30696713;CS-0350454;n-(2-(1h-Indol-3-yl)ethyl)-n-(p-tolyl)formamide;N-[2-(1H-indol-3-yl)ethyl]-N-(4-methylphenyl)formamide

Suppliers and Price of N-[2-(1H-indol-3-yl)ethyl]-N-(4-methylphenyl)formamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-(2-INDOL-3-YL ETHYL)(4-METHYLPHENYL)FORMAMIDE 95.00%
10MG
$ 618.50

American Custom Chemicals Corporation
N-(2-INDOL-3-YL ETHYL)(4-METHYLPHENYL)FORMAMIDE 95.00%
1MG
$ 586.97

Total 3 raw suppliers

Chemical Property of N-[2-(1H-indol-3-yl)ethyl]-N-(4-methylphenyl)formamide

Chemical Property:

Boiling Point:541.8±43.0 °C(Predicted)
PKA:15.12±0.46(Predicted)
PSA：36.10000
Density:1.180±0.06 g/cm3(Predicted)
LogP:4.31770
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:278.141913202
Heavy Atom Count:21
Complexity:338

Purity/Quality:

97% ^*data from raw suppliers

N-(2-INDOL-3-YL ETHYL)(4-METHYLPHENYL)FORMAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N(CCC2=CNC3=CC=CC=C32)C=O

Technology Process of N-[2-(1H-indol-3-yl)ethyl]-N-(4-methylphenyl)formamide

There total 2 articles about N-[2-(1H-indol-3-yl)ethyl]-N-(4-methylphenyl)formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 61-54-1
tryptamine

: 874-60-2
4-methyl-benzoyl chloride

: 881597-49-5
N-(2-(1H-indol-3-yl)ethyl)-4-methylbenzamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.3390/molecules23010102

Reference yield: 57.0%

: 61-54-1
tryptamine

: 13664-98-7
2,2-dibromo-1-(4-methylphenyl)ethanone

: 1284150-89-5
N-(2-(1H-indol-3-yl)ethyl)-2-oxo-2-(p-tolyl)acetamide

: 881597-49-5
N-(2-(1H-indol-3-yl)ethyl)-4-methylbenzamide

Guidance literature:: 2,2-dibromo-1-(4-methylphenyl)ethanone; With sodium iodide; In dimethyl sulfoxide; at 25 - 45 ℃; Inert atmosphere;

tryptamine; With triethylamine; In dimethyl sulfoxide; at 25 - 45 ℃; Inert atmosphere;

With Cumene hydroperoxide; In hexane; dimethyl sulfoxide; at 25 - 45 ℃; Inert atmosphere;
DOI:10.3762/bjoc.10.45