2-[(4-oxo-1,4-dihydroquinazolin-2-yl)sulfanyl]propanoic acid

Base Information

Chemical Name:2-[(4-oxo-1,4-dihydroquinazolin-2-yl)sulfanyl]propanoic acid
CAS No.:328977-86-2
Molecular Formula:C11H10N2O3S
Molecular Weight:250.27
Hs Code.:2933990090

Synonyms:CHEMBRDG-BB 6872825;2-((4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)THIO)PROPANOIC ACID;2-(4-OXO-3,4-DIHYDRO-QUINAZOLIN-2-YLSULFANYL)-PROPIONIC ACID;AKOS KUBRG0000021;ZERENEX E/7120157;2-[(4-oxo-3,4-dihydroquinazolin-2-yl)thio]propanoic acid(SALTDATA: FREE)

Suppliers and Price of 2-[(4-oxo-1,4-dihydroquinazolin-2-yl)sulfanyl]propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-(4-Oxo-1,4-dihydro-quinazolin-2-ylsulfanyl)-propionic acid
1g
$ 378.00

Crysdot
2-((4-Oxo-1,4-dihydroquinazolin-2-yl)thio)propanoicacid 97%
5g
$ 874.00

Chemenu
2-((4-Oxo-1,4-dihydroquinazolin-2-yl)thio)propanoicacid 97%
5g
$ 825.00

ChemBridge Corporation
2-[(4-oxo-3,4-dihydroquinazolin-2-yl)thio]propanoicacid 95%
1 g
$ 70.00

American Custom Chemicals Corporation
2-((4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)THIO)PROPANOIC ACID 95.00%
10G
$ 1905.75

American Custom Chemicals Corporation
2-((4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)THIO)PROPANOIC ACID 95.00%
5G
$ 1316.70

American Custom Chemicals Corporation
2-((4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)THIO)PROPANOIC ACID 95.00%
1G
$ 866.25

Total 2 raw suppliers

Chemical Property of 2-[(4-oxo-1,4-dihydroquinazolin-2-yl)sulfanyl]propanoic acid

Chemical Property:

Vapor Pressure:1.14E-09mmHg at 25°C
Boiling Point:470.8°C at 760 mmHg
Flash Point:238.5°C
PSA：108.35000
Density:1.49g/cm³
LogP:1.48830

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Oxo-1,4-dihydro-quinazolin-2-ylsulfanyl)-propionic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-[(4-oxo-1,4-dihydroquinazolin-2-yl)sulfanyl]propanoic acid

There total 4 articles about 2-[(4-oxo-1,4-dihydroquinazolin-2-yl)sulfanyl]propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 13906-09-7
2-thioxo-2,3-dihydro-1H-quinazolin-4-one

: 598-72-1,10327-08-9
2-Bromopropionic acid

: 328977-86-2
2-(4-oxo-3,4-dihydroquinazolin-2-ylsulfanyl)propionic acid

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 75 ℃; for 12h;
DOI:10.1021/acsinfecdis.7b00275

Reference yield:

: 598-72-1,10327-08-9
2-Bromopropionic acid

: 13906-09-7
2-mercapto-3H-quinazolin-4-one

: 328977-86-2
2-(4-oxo-3,4-dihydroquinazolin-2-ylsulfanyl)propionic acid

Guidance literature:: With sodium hydroxide; In water; at 20 ℃;

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 328977-86-2
2-(4-oxo-3,4-dihydroquinazolin-2-ylsulfanyl)propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 3 h / 180 °C

2: triethylamine / N,N-dimethyl-formamide / 12 h / 75 °C

With triethylamine; In N,N-dimethyl-formamide;
DOI:10.1021/acsinfecdis.7b00275