2-Oxopiperidine-4-methano...

Base Information

Chemical Name:2-Oxopiperidine-4-methano...
CAS No.:53611-47-5
Molecular Formula:C₆H₁₁NO₂
Molecular Weight:129.159
Hs Code.:2933790090
Mol file:53611-47-5.mol

Synonyms:2-Oxopiperidine-4-methano...;2-Oxopiperidine-4-Methanol;4-(hydroxymethyl)piperidin-2-one

Suppliers and Price of 2-Oxopiperidine-4-methano...

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Hydroxymethyl)-2-piperidinone
250mg
$ 640.00

SynQuest Laboratories
2-Oxopiperidine-4-methanol
1 g
$ 675.00

Matrix Scientific
2-Oxopiperidine-4-methanol >95%
250mg
$ 240.00

Matrix Scientific
2-Oxopiperidine-4-methanol >95%
500mg
$ 361.00

Matrix Scientific
2-Oxopiperidine-4-methanol >95%
1g
$ 555.00

Crysdot
4-(Hydroxymethyl)piperidin-2-one 95+%
1g
$ 470.00

Chemenu
4-(hydroxymethyl)piperidin-2-one 97%
1g
$ 418.00

Chemenu
4-(hydroxymethyl)piperidin-2-one 97%
5g
$ 1265.00

American Custom Chemicals Corporation
4-(HYDROXYMETHYL)PIPERIDIN-2-ONE 95.00%
5MG
$ 450.11

Ambeed
4-(Hydroxymethyl)piperidin-2-one 98+%
1g
$ 370.00

Total 17 raw suppliers

Chemical Property of 2-Oxopiperidine-4-methano...

Chemical Property:

Boiling Point:346.4±15.0 °C(Predicted)
PKA:14.67±0.10(Predicted)
PSA：49.33000
Density:1.098±0.06 g/cm3(Predicted)
LogP:-0.16630

Purity/Quality:

99%, ^*data from raw suppliers

4-(Hydroxymethyl)-2-piperidinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4-(Hydroxymethyl)-2-piperidinone is used in the synthesis of cyclopropyl-amide as LSD1 and HDAC6 inhibitors.

Technology Process of 2-Oxopiperidine-4-methano...

There total 2 articles about 2-Oxopiperidine-4-methano... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 25504-47-6
methyl (RS)-2-oxopiperidine-4-carboxylate

: 53611-47-5
4-(hydroxymethyl)piperidin-2-one

Guidance literature:: With diisobutylaluminium hydride; In tetrahydrofuran; at -30 - 20 ℃;

Reference yield:

: 24537-50-6
(RS)-2-oxopiperidine-4-carboxylic acid

: 53611-47-5
4-(hydroxymethyl)piperidin-2-one

Guidance literature:: (RS)-2-oxopiperidine-4-carboxylic acid; With 4-methyl-morpholine; chloroformic acid ethyl ester; In tetrahydrofuran; at -10 - 0 ℃; for 0.75h;

With sodium tetrahydroborate; sodium hydroxide; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

Reference yield:

: 53611-47-5
4-(hydroxymethyl)piperidin-2-one

: (S)-pyridin-2-yl 1-(4-fluorophenyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

: (1S)-(2-oxopiperidin-4-yl)methyl 1-(4-fluorophenyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

Guidance literature:: 4-(hydroxymethyl)piperidin-2-one; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 0.5h;

(S)-pyridin-2-yl 1-(4-fluorophenyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate; In N,N-dimethyl-formamide; mineral oil; at 0 - 65 ℃; for 2h;