L-(2-15N)Glutamine

Base Information

Chemical Name:L-(2-15N)Glutamine
CAS No.:80143-57-3
Molecular Formula:C₅H₁₀N₂O₃
Molecular Weight:147.139
Hs Code.:
UNII:905V50H511
DSSTox Substance ID:DTXSID20472740
Nikkaji Number:J728.849B
Mol file:80143-57-3.mol

Synonyms:80143-57-3;L-(2-15N)Glutamine;2-15N-Glutamine;Glutamine 2-N-15;L-Glutamine 15N;905V50H511;UNII-905V50H511;(2S)-5-Amino-2-(15N)azanyl-5-oxopentanoic acid;L-Glutamine-(amine-15N);L-Glutamine-15N;L-Glutamine-(1)?N;L-Glutamine(alpha-15N);2-15N GLUTAMINE;L-GLUTAMINE-N2-15N;HY-N0390S;L-(N~2~-~15~N)Glutamine;DTXSID20472740;MS-22835;CS-0226273;L-Glutamine-(amine-15N), 98 atom % 15N

Suppliers and Price of L-(2-15N)Glutamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
L-Glutamine-15N
100mg
$ 220.00

Sigma-Aldrich
L-Glutamine-(amine-15N) 98 atom %
1g
$ 764.00

American Custom Chemicals Corporation
L-GLUTAMINE (ALPHA-15N) 95.00%
1G
$ 1429.84

Total 7 raw suppliers

Chemical Property of L-(2-15N)Glutamine

Chemical Property:

Melting Point:185 °C (dec.)(lit.)
PSA：106.41000
LogP:0.06440
XLogP3:-3.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:147.06617708
Heavy Atom Count:10
Complexity:146

Purity/Quality:

98% by HPLC; 98% atom 15N ^*data from raw suppliers

L-Glutamine-15N ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CC(=O)N)C(C(=O)O)N
Isomeric SMILES:C(CC(=O)N)[C@@H](C(=O)O)[15NH2]

Technology Process of L-(2-15N)Glutamine

There total 2 articles about L-(2-15N)Glutamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 21160-87-2
¹⁵N-glutamic acid

: 80143-57-3
(α-15N)-L-glutamine

Guidance literature:: With ammonium chloride; ATP; magnesium chloride; 1H-imidazole; glutamine synthetase; In water; at 38 ℃; for 24h; pH=7.1;
DOI:10.1023/A:1012417532363

Reference yield:

: 554428-56-7,108395-12-6,1202063-54-4,206983-94-0,95388-01-5
(2S,3S,4R)-[3,4-(2)H2;1,2,3,4,5-(13)C5;2-(15)N]glutamic acid

: 554428-63-6,80143-57-3,184161-19-1,159680-32-7
(2S,3S,4R)-[1,2,3,4,5-13C5;2,5-13N2;3,4-2H2]glutamine

Guidance literature:: (2S,3S,4R)-[3,4-⁽²⁾H₂;1,2,3,4,5-⁽¹³⁾C₅;2-⁽¹⁵⁾N]glutamic acid; With sulfuric acid; In methanol; at -5 - 20 ℃; for 3h;

With carbon disulfide; ammonia; at 0 - 20 ℃; for 240h;

Reference yield:

: 59681-32-2,80143-57-3,184161-19-1,159680-32-7,204451-48-9,494783-18-5
¹³C₅-¹⁵N₂-L-glutamine

: 108395-12-6,1202063-54-4,206983-94-0,95388-01-5
1,2,3,4,5-^⁽¹³⁾C₅,^⁽¹⁵⁾N-L-glutamic acid

Guidance literature:: With glutaminase; 6-diazo-5-oxo-L-norleucine; In water; at 4 ℃; for 0.333333h; Enzymatic reaction;
DOI:10.1021/acschembio.6b00493