(1S)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE

Base Information

Chemical Name:(1S)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE
CAS No.:1213137-26-8
Molecular Formula:C9H10F3NO
Molecular Weight:205.18
Hs Code.:
Mol file:1213137-26-8.mol

Synonyms:(1S)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE;(S)-2,2,2-TRIFLUORO-1-(3-METHOXY-PHENYL)-ETHYLAMINE

Suppliers and Price of (1S)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

JR MediChem
Benzenemethanamine,3-methoxy-a-(trifluoromethyl)-,(aS)- 96%
1g
$ 780.00

Chemenu
(S)-2,2,2-Trifluoro-1-(3-methoxyphenyl)ethanamine 95%
1g
$ 439.00

Alichem
(S)-2,2,2-Trifluoro-1-(3-methoxyphenyl)ethanamine
1g
$ 470.00

AK Scientific
(1S)-2,2,2-Trifluoro-1-(3-methoxyphenyl)ethylamine
1g
$ 1237.00

AK Scientific
(1S)-2,2,2-Trifluoro-1-(3-methoxyphenyl)ethylamine
250mg
$ 531.00

Total 8 raw suppliers

Chemical Property of (1S)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE

Chemical Property:

PSA：35.25000
LogP:2.95760

Purity/Quality:

99% ^*data from raw suppliers

Benzenemethanamine,3-methoxy-a-(trifluoromethyl)-,(aS)- 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1S)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE

There total 4 articles about (1S)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1334287-98-7
(S)-4-methoxy-N-(2,2,2-trifluoro-1-(3-methoxyphen-yl)ethyl)aniline

: 1213137-26-8,856758-72-0
(S)-2,2,2-trifluoro-1-(3-methoxyphenyl)ethan-1-amine

Guidance literature:: With sulfuric acid; periodic acid; In water; acetonitrile; at 20 ℃; for 24h; optical yield given as %ee;
DOI:10.1002/anie.201103240

Reference yield: 64.0%

: 1223578-81-1
(R(S),S)-N-[2,2,2-trifluoro-1-(3-methoxyphenyl)ethyl]-2-propanesulfinamide

: 1213137-26-8,856758-72-0
(S)-2,2,2-trifluoro-1-(3-methoxyphenyl)ethan-1-amine

Guidance literature:: With trifluoroacetic acid; In methanol; at 0 ℃; Inert atmosphere;
DOI:10.1002/ejoc.200901158

Reference yield:

: 30724-22-2
2,2,2-trifluoro-1-(3-methoxyphenyl)ethanone

: 1213137-26-8,856758-72-0
(S)-2,2,2-trifluoro-1-(3-methoxyphenyl)ethan-1-amine

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / 24 h / 120 °C

2: (R)-3,3'-bis[3,5-di(trifluoromethyl)phenyl]-1,1'-binaphthyl phosphate; 2-(4-nitrophenyl)-2,3-dihydrobenzothiazole / dichloromethane / 24 h / 55 °C / Inert atmosphere

3: sulfuric acid; periodic acid / water; acetonitrile / 24 h / 20 °C

With (R)-3,3'-bis[3,5-di(trifluoromethyl)phenyl]-1,1'-binaphthyl phosphate; 2-(4-nitrophenyl)-2,3-dihydrobenzothiazole; sulfuric acid; periodic acid; In dichloromethane; water; toluene; acetonitrile;
DOI:10.1002/anie.201103240