1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole

Base Information

• Chemical Name: 1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole
• CAS No.: 1278579-60-4
• Molecular Formula: C₁₇H₂₉B₂NO₄
• Molecular Weight: 333.044
• Hs Code.: 2934999090
• Mol file: 1278579-60-4.mol

Synonyms:1-Methyl-1H-pyrrole-2,4-diboronic acid, pinacol ester;1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole

Chemical Property of 1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole

Chemical Property:

• PSA: 41.85000
• LogP: 1.62350
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

1-Methyl-1H-pyrrole-2,4-diboronicacid,pinacolester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole

There total 5 articles about 1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2,3-dimethyl-2,3-butane diol (76-09-5) + 2,4-di(1,3,2-benzodioxaborolan-2-yl)-1-methyl-pyrrole (1278579-86-4) → 1-methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole (1278579-60-4)

Guidance literature:

With triethylamine; In dichloromethane; for 1h; Inert atmosphere;

DOI:10.1002/anie.201006196

Reference yield: 73.0%

N-Methylpyrrole (96-54-8) + 2,3-dimethyl-2,3-butane diol (76-09-5) + C6H4O2BN(C2H5)3(1+)*AlCl4(1-)=C6H4O2BN(C2H5)3[AlCl4] → 1-methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole (1278579-60-4)

Guidance literature:

With Et₃N; In dichloromethane; byproducts: Et3NH-AlCl4; to borenium cation made in situ (in Schlenk, to soln. Et2N (CH2Cl2) added CatBCl, AlCl3; stirred) at 20°C arene added (CH2Cl2); excess Et3N added; pinacol added; stirred for 192 h;; (11)B (1H) NMR; volatiless remowed under vac; extracted (hexane); filtered through silica; removal of solvent;;

DOI:10.1002/anie.201006196

Reference yield: 35.0%

N-Methylpyrrole (96-54-8) + 2,3-dimethyl-2,3-butane diol (76-09-5) + C10H7BO3 (1086138-68-2) → 1-methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole (1278579-60-4)

Guidance literature:

N-Methylpyrrole; C₁₀H₇BO₃; With 2-Sulfanylpyridine; In toluene; at 180 ℃; for 2h; Microwave irradiation;

2,3-dimethyl-2,3-butane diol; With triethylamine; In toluene; at 20 ℃; for 1h;

DOI:10.1021/jacs.9b04305

upstream raw materials:

N-Methylpyrrole

2,3-dimethyl-2,3-butane diol

2,4-di(1,3,2-benzodioxaborolan-2-yl)-1-methyl-pyrrole

2-chloro-1,3,2-benzodioxaborole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1278579-60-4 1-Methyl-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole

Send

Send

Metric Ton KG G Pound L ML

Send

Send