2-Amino-4-phenyl-5-phenylsulfonyl-1,3-thiazole

Base Information

Chemical Name:2-Amino-4-phenyl-5-phenylsulfonyl-1,3-thiazole
CAS No.:252679-72-4
Molecular Formula:C₁₅H₁₂N₂O₂S₂
Molecular Weight:316.404
Hs Code.:2934100090
DSSTox Substance ID:DTXSID30394085
Nikkaji Number:J1.209.642I
Wikidata:Q82193269
Mol file:252679-72-4.mol

Synonyms:252679-72-4;2-Amino-4-phenyl-5-phenylsulfonyl-1,3-thiazole;5-(benzenesulfonyl)-4-phenyl-1,3-thiazol-2-amine;4-Phenyl-5-(phenylsulfonyl)thiazol-2-amine;2-amino-4-phenyl-5-(phenylsulphonyl)-1,3-thiazole;DTXSID30394085;CKA67972;MFCD03700392;AKOS015854660;4-Phenyl-5-(phenylsulfonyl)thiazole-2-amine;BB 0254051;CS-0450173

Suppliers and Price of 2-Amino-4-phenyl-5-phenylsulfonyl-1,3-thiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Amino-4-phenyl-5-phenylsulfonyl-1,3-thiazole
500mg
$ 283.00

Crysdot
4-Phenyl-5-(phenylsulfonyl)thiazol-2-amine 97%
5g
$ 877.00

AK Scientific
2-Amino-4-phenyl-5-phenylsulfonyl-1,3-thiazole
500mg
$ 354.00

Total 3 raw suppliers

Chemical Property of 2-Amino-4-phenyl-5-phenylsulfonyl-1,3-thiazole

Chemical Property:

Melting Point:192 °C(Solv: ethanol (64-17-5))
Boiling Point:584.7±38.0 °C(Predicted)
PKA:1.16±0.10(Predicted)
PSA：109.67000
Density:1.387±0.06 g/cm3(Predicted)
LogP:4.88710
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:316.03401998
Heavy Atom Count:21
Complexity:437

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-4-phenyl-5-phenylsulfonyl-1,3-thiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(SC(=N2)N)S(=O)(=O)C3=CC=CC=C3

Technology Process of 2-Amino-4-phenyl-5-phenylsulfonyl-1,3-thiazole

There total 4 articles about 2-Amino-4-phenyl-5-phenylsulfonyl-1,3-thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 23128-59-8
ω-bromo-ω-phenylsulfonylacetophenone

: 17356-08-0
thiourea

: 252679-72-4
2-amino-4-phenyl-5-benzenesulfonylthiazole

Guidance literature:: In ethanol; for 1h; Heating;
DOI:10.1002/jhet.5570360412

Reference yield:

: 3406-03-9
2-(phenylsulfonyl)acetophenone

: 252679-72-4
2-amino-4-phenyl-5-benzenesulfonylthiazole

Guidance literature:: Multi-step reaction with 2 steps

1: phenyltrimethylammonium tribromide / acetonitrile / 2 h / 20 °C

2: acetonitrile / 3 h / Heating

With phenyltrimethylammonium tribromide; In acetonitrile; 2: Hantzsch thiazole synthesis;

Reference yield:

: 873-55-2
sodium benzenesulfonate

: 252679-72-4
2-amino-4-phenyl-5-benzenesulfonylthiazole

Guidance literature:: Multi-step reaction with 3 steps

1.1: phenyltrimethylammonium tribromide / acetonitrile / 20 °C

1.2: acetonitrile / 20 °C

2.1: phenyltrimethylammonium tribromide / acetonitrile / 2 h / 20 °C

3.1: acetonitrile / 3 h / Heating

With phenyltrimethylammonium tribromide; In acetonitrile; 3.1: Hantzsch thiazole synthesis;