SUBSTANCE P

Base Information

• Chemical Name: SUBSTANCE P
• CAS No.: 12769-48-1
• Molecular Formula: C63H98N18O13S
• Molecular Weight: 1347.63
• Mol file: 12769-48-1.mol

Synonyms:H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2;H2N-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET;ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2;RPKPQQFFGLM-NH2;RPKPQFFGLM;SUBSTANCE P (HUMAN, BOVINE, RAT, MOUSE);SUBSTANCE P BOVINE;SUBSTANCE P, [D-ARG1, D-PRO2, D-TRP7,9, LEU11]

Chemical Property of SUBSTANCE P

Chemical Property:

• PSA: 541.93000
• Density: 1.42g/cm³
• LogP: 4.19410
• Storage Temp.: -20°C

Purity/Quality:

99%, ^*data from raw suppliers

Substance P ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Substance P is a neurokinin undecapeptide neurotransmitter and neuromodulator.
• Clinical Use: The 5-HT neurons coexpress substance P, and the firing of NE neurons is modulated by substance P. Preclinical studies have supported a role of the substance P–NK1 receptor system in stress-related disorders, which has guided the antidepressant development of centrally active NK1 receptor antagonists, such as aprepitant. The NK1 antagonists are generally well tolerated and exhibit less nausea and sexual dysfunction than some currently used antidepressants.

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