TERT-BUTYL 4-(3-NITROPYRIDIN-4-YLAMINO)PIPERIDINE-1-CARBOXYLATE

Base Information

Chemical Name:TERT-BUTYL 4-(3-NITROPYRIDIN-4-YLAMINO)PIPERIDINE-1-CARBOXYLATE
CAS No.:1067718-07-3
Molecular Formula:C15H22N4O4
Molecular Weight:322.364
Hs Code.:
Mol file:1067718-07-3.mol

Synonyms:TERT-BUTYL 4-(3-NITROPYRIDIN-4-YLAMINO)PIPERIDINE-1-CARBOXYLATE;1-PIPERIDINECARBOXYLIC ACID, 4-[(3-NITRO-4-PYRIDINYL)AMINO]-, 1,1-DIMETHYLETHYL ESTER

Suppliers and Price of TERT-BUTYL 4-(3-NITROPYRIDIN-4-YLAMINO)PIPERIDINE-1-CARBOXYLATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of TERT-BUTYL 4-(3-NITROPYRIDIN-4-YLAMINO)PIPERIDINE-1-CARBOXYLATE

Chemical Property:

PSA：100.28000
LogP:3.33530

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of TERT-BUTYL 4-(3-NITROPYRIDIN-4-YLAMINO)PIPERIDINE-1-CARBOXYLATE

There total 1 articles about TERT-BUTYL 4-(3-NITROPYRIDIN-4-YLAMINO)PIPERIDINE-1-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5435-54-1
4-hydroxy-3-nitropyridine

: 1067718-07-3
tert-butyl 4-((3-nitropyridin-4-yl)amino)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: POCl₃, PCl₅ / 18 h / 130 °C

2: Et₃N / CHCl₃ / 18 h / Heating

With phosphorus pentachloride; triethylamine; trichlorophosphate; In chloroform;
DOI:10.1021/jm950555i

Reference yield:

: 1067718-07-3
tert-butyl 4-((3-nitropyridin-4-yl)amino)piperidine-1-carboxylate

: 185962-07-6
1-(piperidin-4-yl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: palladium on activated charcoal; hydrogen / methanol / 2 h

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 12 h / 20 °C / Inert atmosphere

3: hydrogenchloride / 1,4-dioxane / 16 h / 0 - 20 °C

With hydrogenchloride; palladium on activated charcoal; hydrogen; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; methanol; dichloromethane;