(1aS,1bR,5aS,6aS)-Hexahydro-3-(4-Methoxyphenyl)-oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin

Base Information

Chemical Name:(1aS,1bR,5aS,6aS)-Hexahydro-3-(4-Methoxyphenyl)-oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin
CAS No.:905580-85-0
Molecular Formula:C14H16O4
Molecular Weight:248.279
Hs Code.:
Mol file:905580-85-0.mol

Synonyms:(1aS,1bR,5aS,6aS)-Hexahydro-3-(4-Methoxyphenyl)-oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin;Oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin, hexahydro-3-(4-Methoxyphenyl)-, (1aS,1bR,5aS,6aS)-

Suppliers and Price of (1aS,1bR,5aS,6aS)-Hexahydro-3-(4-Methoxyphenyl)-oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(1aS,1bR,5aS,6aS)-Hexahydro-3-(4-methoxyphenyl)-oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin
25mg
$ 165.00

Medical Isotopes, Inc.
(1aS,1bR,5aS,6aS)-Hexahydro-3-(4-methoxyphenyl)-oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin
250 mg
$ 2200.00

Crysdot
(1AS,1bR,5aS,6aS)-3-(4-methoxyphenyl)hexahydrooxireno[2',3':4,5]cyclopenta[1,2-d][1,3]dioxine 97%
1g
$ 1191.00

Total 4 raw suppliers

Chemical Property of (1aS,1bR,5aS,6aS)-Hexahydro-3-(4-Methoxyphenyl)-oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin

Chemical Property:

Boiling Point:385.6±42.0 °C(Predicted)
PSA：40.22000
Density:1.236±0.06 g/cm3(Predicted)
LogP:1.89650
Solubility.:Dichloromethane, Ethyl Acetate, Methanol

Purity/Quality:

97% ^*data from raw suppliers

(1aS,1bR,5aS,6aS)-Hexahydro-3-(4-methoxyphenyl)-oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (1aS,1bR,5aS,6aS)-Hexahydro-3-(4-Methoxyphenyl)-oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin is used in the preparation of nucleoside derivatives as antitumor agents, E1 activating enzymes and MLN4924, an inhibitor of NEDD8-activating enzyme.

Technology Process of (1aS,1bR,5aS,6aS)-Hexahydro-3-(4-Methoxyphenyl)-oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin

There total 2 articles about (1aS,1bR,5aS,6aS)-Hexahydro-3-(4-Methoxyphenyl)-oxireno[4,5]cyclopenta[1,2-d][1,3]dioxin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 905580-84-9
(1R,2R,3S,5S)-3-(Hydroxymethyl)-6-oxabicyclo[3.1.0]hexan-2-ol

: 2186-92-7
p-Anisaldehyde dimethyl acetal

: 905580-85-0
(1aS,1bR,5aS,6aS)-3-(4-Methoxyphenyl)hexahydrooxireno[4,5]-cyclopenta[1,2-d][1,3]dioxine

Guidance literature:: With pyridinium p-toluenesulfonate; In dichloromethane; at 0 - 20 ℃;

Reference yield:

: 151765-20-7
(1S,5S)-5-hydroxymethyl-2-cyclopenten-1-ol

: 905580-85-0
(1aS,1bR,5aS,6aS)-3-(4-Methoxyphenyl)hexahydrooxireno[4,5]-cyclopenta[1,2-d][1,3]dioxine

Guidance literature:: Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 0 - 23 °C

2: pyridinium p-toluenesulfonate / dichloromethane / 0 - 23 °C

With pyridinium p-toluenesulfonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

Reference yield: 93.0%

: 905580-85-0
(1aS,1bR,5aS,6aS)-3-(4-Methoxyphenyl)hexahydrooxireno[4,5]-cyclopenta[1,2-d][1,3]dioxine

: 4786-75-8
4-(benzylthio)-7H-pyrrolo[2,3-d]pyrimidine

: 945950-11-8
(4aS,6R,7S,7aR)-6-[4-(Benzylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-(4-methoxyphenyl)hexahydrocyclopenta[d][1,3]dioxin-7-ol

Guidance literature:: 4-(benzylthio)-7H-pyrrolo[2,3-d]pyrimidine; With lithium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide; at 60 ℃; for 0.166667h;

(1aS,1bR,5aS,6aS)-3-(4-Methoxyphenyl)hexahydrooxireno[4,5]-cyclopenta[1,2-d][1,3]dioxine; In tetrahydrofuran; N,N-dimethyl-formamide; at 110 ℃; for 6h;