4-(TRIFLUOROMETHYL)PYRIMIDINE-2-CARBOXYLIC ACID

Base Information

Chemical Name:4-(TRIFLUOROMETHYL)PYRIMIDINE-2-CARBOXYLIC ACID
CAS No.:1000931-46-3
Molecular Formula:C6H3F3N2O2
Molecular Weight:192
Hs Code.:
Mol file:1000931-46-3.mol

Synonyms:4-(TRIFLUOROMETHYL)PYRIMIDINE-2-CARBOXYLIC ACID;4-(trifluoromethyl)-2-Pyrimidinecarboxylic acid

Suppliers and Price of 4-(TRIFLUOROMETHYL)PYRIMIDINE-2-CARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Trifluoromethyl)-2-pyrimidinecarboxylicAcid
1g
$ 200.00

Matrix Scientific
4-(Trifluoromethyl)pyrimidine-2-carboxylic acid 95%
1g
$ 1814.00

Matrix Scientific
4-(Trifluoromethyl)pyrimidine-2-carboxylic acid 95%
250mg
$ 648.00

Crysdot
4-(Trifluoromethyl)pyrimidine-2-carboxylicacid 95+%
250mg
$ 232.00

Crysdot
4-(Trifluoromethyl)pyrimidine-2-carboxylicacid 95+%
1g
$ 580.00

Chemenu
4-(Trifluoromethyl)pyrimidine-2-carboxylicacid 95%
1g
$ 542.00

American Custom Chemicals Corporation
4-(TRIFLUOROMETHYL)PYRIMIDINE-2-CARBOXYLIC ACID 95.00%
1G
$ 1587.60

AK Scientific
4-(Trifluoromethyl)pyrimidine-2-carboxylicacid
1g
$ 2498.00

AK Scientific
4-(Trifluoromethyl)pyrimidine-2-carboxylicacid
250mg
$ 924.00

Total 11 raw suppliers

Chemical Property of 4-(TRIFLUOROMETHYL)PYRIMIDINE-2-CARBOXYLIC ACID

Chemical Property:

PSA：63.08000
LogP:1.19360
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4-(Trifluoromethyl)-2-pyrimidinecarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4-(Trifluoromethyl)-2-pyrimidinecarboxylic Acid is used as a reactant in the preparation of piperazine derivatives to be used as mGluR5 receptor positive allosteric modulators.

Technology Process of 4-(TRIFLUOROMETHYL)PYRIMIDINE-2-CARBOXYLIC ACID

There total 1 articles about 4-(TRIFLUOROMETHYL)PYRIMIDINE-2-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1206459-86-0
4-(trifluoromethyl)pyrimidine-2-carbonitrile

: 1000931-46-3
4-(trifluoromethyl)pyrimidine-2-carboxylic acid

Guidance literature:: With hydrogenchloride; water; Reflux;

Reference yield:

: 1000931-46-3
4-(trifluoromethyl)pyrimidine-2-carboxylic acid

: 8-(5-amino-2-methylphenyl)-2',3',5',6'-tetrahydro-3H-spiro[benzo[b][1,4]oxazepine-2,4'-pyran]-4(5H)-one

: N-(4-methyl-3-(4-oxo-2',3',4,5,5',6'-hexahydro-3H-spiro[benzo[b][1,4]oxazepine-2,4'-pyran]-8-yl)phenyl)-4-(trifluoromethyl)pyrimidine-2-carboxamide

Guidance literature:: With triethylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1016/j.ejmech.2021.114040