3-Ethenyl-2,5-dihydro-2,2,5,5-tetraMethyl-1H-pyrrol-1-yloxy

Base Information

• Chemical Name: 3-Ethenyl-2,5-dihydro-2,2,5,5-tetraMethyl-1H-pyrrol-1-yloxy
• CAS No.: 105843-07-0
• Molecular Formula: C10H16NO *
• Molecular Weight: 166.24014
• Mol file: 105843-07-0.mol

Synonyms:1-Oxyl-2,2,5,5,-tetraMethyl-3-vinyl-3-pyrroline;3-Ethenyl-2,5-dihydro-2,2,5,5-tetraMethyl-1H-pyrrol-1-yloxy

Chemical Property of 3-Ethenyl-2,5-dihydro-2,2,5,5-tetraMethyl-1H-pyrrol-1-yloxy

Chemical Property:

• PSA: 3.24000
• LogP: 2.25500

Purity/Quality:

99% ^*data from raw suppliers

1-Oxyl-2,2,5,5,-tetramethyl-3-vinyl-?3-pyrroline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-Oxyl-2,2,5,5,-tetramethyl-3-vinyl-△3-pyrroline is a spin-labeled reagent used in the preparation of spin-labeled analogs of biological active compounds such as: Morphine, Nalorphine, Barbituric acid, Choline and Acetylcholine. 1-Oxyl-2,2,5,5,-tetramethyl-3-vinyl-?3-pyrroline is a spin-labeled reagent used in the preparation of spin-labeled analogs of biological active compounds such as: Morphine, Nalorphine, Barbituric acid, Choline and Acetylcholine.

Technology Process of 3-Ethenyl-2,5-dihydro-2,2,5,5-tetraMethyl-1H-pyrrol-1-yloxy

There total 4 articles about 3-Ethenyl-2,5-dihydro-2,2,5,5-tetraMethyl-1H-pyrrol-1-yloxy which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

3-formyl-2,2,5,5-tetramethyl-pyrroline-1-oxyl (71051-83-7) + methyl-triphenylphosphonium iodide (2065-66-9) → 1-oxyl-3-vinyl-2,2,5,5-tetramethyl-3-pyrroline (105843-07-0)

Guidance literature:

With potassium carbonate; In 1,4-dioxane; for 24h; Heating;

Reference yield:

2,2,5,5-Tetramethyl-3-vinyl-2,5-dihydro-pyrrol-1-ol; hydrochloride (105843-08-1) → 1-oxyl-3-vinyl-2,2,5,5-tetramethyl-3-pyrroline (105843-07-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / K₂CO₃ / CHCl₃ / 0.33 h

2: 1.) 1N aq. NaOH, 2.) PbO₂ / 1.) methanol, 30 min, 2.) 10 min, chloroform

With sodium hydroxide; potassium carbonate; lead dioxide; In chloroform;

Reference yield:

2,2,5,5-Tetramethyl-3-vinyl-2,5-dihydro-pyrrol-1-ol (773808-83-6) → 1-oxyl-3-vinyl-2,2,5,5-tetramethyl-3-pyrroline (105843-07-0)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / CHCl₃ / 0.33 h

2: 1.) 1N aq. NaOH, 2.) PbO₂ / 1.) methanol, 30 min, 2.) 10 min, chloroform

With sodium hydroxide; potassium carbonate; lead dioxide; In chloroform;

upstream raw materials:

3-formyl-2,2,5,5-tetramethyl-pyrroline-1-oxyl

methyl-triphenylphosphonium iodide

N-acetoxy-3-vinyl-2,2,5,5-tetramethyl-3-pyrroline

2,2,5,5-Tetramethyl-3-vinyl-2,5-dihydro-pyrrol-1-ol; hydrochloride