DIMETHYL L-TARTRATE CYCLIC SULFATE

Base Information

• Chemical Name: DIMETHYL L-TARTRATE CYCLIC SULFATE
• CAS No.: 117470-90-3
• Molecular Formula: C₆H₈O₈S
• Molecular Weight: 240.191
• Mol file: 117470-90-3.mol

Synonyms:DIMETHYL L-TARTRATE CYCLIC SULFATE;DIMETHYL (4R, 5R)-1,3,2-DIOXATHIOLANE-4,5-DICARBOXYLATE 2,2-DIOXIDE;(4R,5R)-DIMETHYL-1,3,2-DIOXOTHIOLANE-4,5-DICARBOXYLATE-2,2-DIOXIDE;DIMETHYL (4R,5R)-1,3,2-DIOXATHIOLANE-4,5 -DICA.LA.2,2-DIOXIDE;(-)-dimethyl 2,3-o-sulfonyl-l-tartrate;dimethyl 1,3,2-dioxathiolane-4,5-dicarboxylate 2,2-dioxide;(-)-Dimethyl 2,3-O-sulfonyl-L-tartrate, Dimethyl L-tartrate cycl-sulfate

Chemical Property of DIMETHYL L-TARTRATE CYCLIC SULFATE

Chemical Property:

• Vapor Pressure: 1.37E-05mmHg at 25°C
• Melting Point: 68-71 °C(lit.)
• Boiling Point: 367.4°C at 760 mmHg
• Flash Point: 176°C
• PSA: 113.58000
• Density: 1.573g/cm³
• LogP: -0.55800
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

Dimethyl (4R,5R)-1,3,2-dioxathiolane-4,5-dicarboxylate 2,2-dioxide 97% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIMETHYL L-TARTRATE CYCLIC SULFATE

There total 2 articles about DIMETHYL L-TARTRATE CYCLIC SULFATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl L-tartrate (608-68-4) → (4R,5R)-2,2-Dioxo-2λ6-[1,3,2]dioxathiolane-4,5-dicarboxylic acid dimethyl ester (117470-90-3)

Guidance literature:

With thionyl chloride; In tetrachloromethane; at 90 ℃; for 6h;

DOI:10.1016/j.tetlet.2009.09.072

Reference yield:

Dimethyl D-tartrate (13171-64-7) → dimethyl L-tartrate 2,3-cyclic sulfate (127854-46-0,117470-90-3)

Guidance literature:

With ruthenium trichloride; sodium periodate; thionyl chloride; Yield given. Multistep reaction; 1.) CCl₄, 60 deg C, 2.) CH₃CN/H₂O, 25 deg C;

DOI:10.1021/ja00230a045

Reference yield:

(4R,5R)-2,2-Dioxo-2λ6-[1,3,2]dioxathiolane-4,5-dicarboxylic acid dimethyl ester (117470-90-3) → dimethyl (2S,3R)-2-bromo-3-hydroxysuccinate (109874-90-0,256530-26-4)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium bromide / tetrahydrofuran / 2 h / 25 °C

2: sulfuric acid; water / diethyl ether / 12 h

With sulfuric acid; water; lithium bromide; In tetrahydrofuran; diethyl ether;

DOI:10.1016/j.tetlet.2012.10.120

upstream raw materials:

Dimethyl D-tartrate

dimethyl L-tartrate

Downstream raw materials:

dimethyl (2S,3R)-2-bromo-3-hydroxysuccinate

2-amino-3-hydroxy-succinic acid dimethyl ester