(-)-(14alpha)-Dihydrovinpocetine

Base Information

Chemical Name:(-)-(14alpha)-Dihydrovinpocetine
CAS No.:57327-92-1
Molecular Formula:C22H28N2O2
Molecular Weight:352.47
Hs Code.:2939800000
UNII:1E09UMT0FC
DSSTox Substance ID:DTXSID001100499
Nikkaji Number:J675.684K
Wikidata:Q27252308
Mol file:57327-92-1.mol

Synonyms:57327-92-1;(-)-Dihydroapovincaminic acid ethyl ester;(-)-(14alpha)-Dihydrovinpocetine;Dihydrovinpocetine, (-)-(14alpha)-;UNII-1E09UMT0FC;1E09UMT0FC;(-)-(14alpha)-Dihydrovinpocetine-d5;1H-Indolo(3,2,1-de)pyrido(3,2,1-ij)(1,5)naphthyridine-12-carboxylic acid, 13a-ethyl-2,3,5,6,12,13,13a,13b-octahydro-, ethyl ester, (12R,13aS,13bS)-;Ethyl (12R,13aS,13bS)-13a-ethyl-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo(3,2,1-de)pyrido(3,2,1-ij)(1,5)naphthyridine-12-carboxylate;ethyl (15S,17R,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate;1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid, 13a-ethyl-2,3,5,6,12,13,13a,13b-octahydro-, ethyl ester, (12R,13aS,13bS)-;(?)-Dihydrovinpocetine;SCHEMBL10571107;DTXSID001100499;(-)-(14.ALPHA.)-DIHYDROVINPOCETINE;DIHYDROVINPOCETINE, (-)-(14.ALPHA.)-;Q27252308

Suppliers and Price of (-)-(14alpha)-Dihydrovinpocetine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(-)-DihydroapovincaminicAcidEthylEster
100mg
$ 1865.00

TRC
(-)-DihydroapovincaminicAcidEthylEster
25mg
$ 550.00

Total 11 raw suppliers

Chemical Property of (-)-(14alpha)-Dihydrovinpocetine

Chemical Property:

Boiling Point:497.4±45.0 °C(Predicted)
PKA:8.66±0.60(Predicted)
PSA：34.47000
Density:1.29±0.1 g/cm3(Predicted)
LogP:4.17650
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:352.215078140
Heavy Atom Count:26
Complexity:566

Purity/Quality:

NLT 98% ^*data from raw suppliers

(-)-DihydroapovincaminicAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)C(=O)OCC
Isomeric SMILES:CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4[C@H](C2)C(=O)OCC
Uses (-)-Dihydroapovincaminic Acid Ethyl Ester, can be used as a chiral modifier in enantioselective heterogeneous catalytic hydrogenations. It is also structurally related to Vinpocetine (V332500), a Vasodilator (cerebral). (-)-Dihydroapovincaminic Acid Ethyl Ester, can be used as a chiral modifier in enantioselective heterogeneous catalytic hydrogenations. It is also structurally related to Vinpocetine (V332500), a Vasodilator (cerebral). Vinpocetine USP Related Compound D

Technology Process of (-)-(14alpha)-Dihydrovinpocetine

There total 4 articles about (-)-(14alpha)-Dihydrovinpocetine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 77549-94-1,80038-06-8
3β-apovincaminic acid ethyl ester

: 57327-92-1,57517-54-1,59684-94-5,68779-70-4,68779-72-6,78216-19-0,96245-05-5,96245-06-6
14-Ethoxycarbonyl-14,15-dihydro-3β,16α-eburnamenin

Guidance literature:: With ammonium hydroxide; formic acid; palladium; In N-methyl-acetamide; ethanol; dichloromethane; water;

Reference yield:

: 42971-09-5,80038-06-8
Vinpocetine

: 57327-92-1
3α-deoxyvincaminic acid ethyl ester

: 57517-54-1
3α-deoxyepivincaminic acid ethyl ester

Guidance literature:: With hydrogen; Rh on carbon; In methanol; at 25 ℃; under 4500.4 Torr; Yield given. Yields of byproduct given;
DOI:10.1016/0957-4166(95)00317-I