3-Phenyl-N-(trifluoroacetyl)-L-alanine butyl ester

Base Information

• Chemical Name: 3-Phenyl-N-(trifluoroacetyl)-L-alanine butyl ester
• CAS No.: 1550-95-4
• Molecular Formula: C₁₅H₁₈F₃NO₃
• Molecular Weight: 317.308
• Mol file: 1550-95-4.mol

Synonyms:3-Phenyl-N-(trifluoroacetyl)-L-alanine butyl ester;N-(Trifluoroacetyl)-L-phenylalanine butyl ester

Chemical Property of 3-Phenyl-N-(trifluoroacetyl)-L-alanine butyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Phenyl-N-(trifluoroacetyl)-L-alanine butyl ester

There total 4 articles about 3-Phenyl-N-(trifluoroacetyl)-L-alanine butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-iodo-butane (542-69-8) + N-trifluoroacetyl-L-phenylalanine (350-09-4) → (S)-(-)-butyl N-(trifluoroacetyl)phenylalaninate (52574-47-7,1550-95-4)

Guidance literature:

With sodium hydrogencarbonate; In N,N-dimethyl-formamide; for 24h;

DOI:10.1021/jo00264a033

Reference yield:

1-iodo-butane (542-69-8) + (R)-N-(trifluoroacetyl)phenylalanine (7656-14-6) → (R)-(+)-butyl N-(trifluoroacetyl)phenylalaninate (73366-06-0,1550-95-4)

Guidance literature:

With sodium hydrogencarbonate; In N,N-dimethyl-formamide; for 24h;

DOI:10.1021/jo00264a033

Reference yield:

N-Trifluoracetyl-phenylalanin-n-butylester (88494-58-0,1550-95-4) → (S)-(-)-butyl N-(trifluoroacetyl)phenylalaninate (52574-47-7,1550-95-4) + (R)-(+)-butyl N-(trifluoroacetyl)phenylalaninate (73366-06-0,1550-95-4)

Guidance literature:

With (R,R)-BINOL²-C/PDAN-based chiral covalent organic frameworks coated open tubular GC column; Reagent/catalyst; Resolution of racemate;

DOI:10.1021/jacs.1c11051

upstream raw materials:

1-iodo-butane

N-trifluoroacetyl-L-phenylalanine

N-Trifluoracetyl-phenylalanin-n-butylester

(R)-N-(trifluoroacetyl)phenylalanine

Downstream raw materials:

(S)-(-)-butyl N-(trifluoroacetyl)phenylalaninate

(R)-(+)-butyl N-(trifluoroacetyl)phenylalaninate