4-Acetylpicolinic acid

Base Information

• Chemical Name: 4-Acetylpicolinic acid
• CAS No.: 20857-22-1
• Molecular Formula: C8H7NO3
• Molecular Weight: 165.14608
• Hs Code.: 2933399090
• Mol file: 20857-22-1.mol

Synonyms:4-Acetylpicolinic acid

Chemical Property of 4-Acetylpicolinic acid

Chemical Property:

• PSA: 67.26000
• LogP: 0.98240
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4-Acetylpicolinicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Acetylpicolinic acid

There total 2 articles about 4-Acetylpicolinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

4-acetyl-2-(ethoxycarbonyl)pyridine (135450-67-8) → 4-acetyl-pyridine-2-carboxylic acid (20857-22-1)

Guidance literature:

4-acetyl-2-(ethoxycarbonyl)pyridine; With sodium hydroxide; water; at 20 ℃; for 2h;

With citric acid; In water; pH=2;

Reference yield:

→ 4-acetyl-pyridine-2-carboxylic acid (20857-22-1)

Guidance literature:

2-Formyl-4-acetyl-pyridin, Oxid.;

Reference yield:

2,3,4,5,6-pentafluorophenol (771-61-9) + 4-acetyl-pyridine-2-carboxylic acid (20857-22-1) → C14H6F5NO3 (1163718-38-4)

Guidance literature:

With dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; at 20 ℃; for 2h;

upstream raw materials:

4-acetyl-2-(ethoxycarbonyl)pyridine

Downstream raw materials:

C₁₄H₆F₅NO₃