1,5-Naphthyridine-4-carboxylic acid

Base Information

Chemical Name:1,5-Naphthyridine-4-carboxylic acid
CAS No.:79426-14-5
Molecular Formula:C9H6N2O2
Molecular Weight:174.159
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40507462
Wikidata:Q82363708
Mol file:79426-14-5.mol

Synonyms:1,5-naphthyridine-4-carboxylic acid;79426-14-5;[1,5]NAPHTHYRIDINE-4-CARBOXYLIC ACID;MFCD16652616;SCHEMBL2455911;DTXSID40507462;1,5-naphthyridine-4-carboxylicacid;AMY36807;AKOS005208396;SB38805;SY044921;CS-0341677;EN300-237045;A864863;F1957-0073

Suppliers and Price of 1,5-Naphthyridine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,5-naphthyridine-4-carboxylicacid
25mg
$ 65.00

Matrix Scientific
1,5-Naphthyridine-4-carboxylic acid 95%+
2.500g
$ 1415.00

Matrix Scientific
1,5-Naphthyridine-4-carboxylic acid 95%+
1g
$ 648.00

Matrix Scientific
1,5-Naphthyridine-4-carboxylic acid 95%+
5g
$ 2137.00

Crysdot
1,5-Naphthyridine-4-carboxylicacid 95+%
5g
$ 1965.00

Crysdot
1,5-Naphthyridine-4-carboxylicacid 95+%
1g
$ 610.00

Alichem
1,5-Naphthyridine-4-carboxylicacid
250mg
$ 274.56

AK Scientific
1,5-Naphthyridine-4-carboxylicacid
5g
$ 2934.00

Total 9 raw suppliers

Chemical Property of 1,5-Naphthyridine-4-carboxylic acid

Chemical Property:

Melting Point:168-168.5 °C(Solv: ethanol (64-17-5))
Boiling Point:366.8±22.0 °C(Predicted)
PKA:2.60±0.10(Predicted)
PSA：63.08000
Density:1.421±0.06 g/cm3(Predicted)
LogP:1.32800
Storage Temp.:2-8°C
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:174.042927438
Heavy Atom Count:13
Complexity:208

Purity/Quality:

97% ^*data from raw suppliers

1,5-naphthyridine-4-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=NC=CC(=C2N=C1)C(=O)O

Technology Process of 1,5-Naphthyridine-4-carboxylic acid

There total 5 articles about 1,5-Naphthyridine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 79426-12-3
4-(α-bromo-α,α-dicarbethoxy)methyl-1,5-naphthyridine 1-oxide

: 79426-14-5
1,5-naphthyridine-4-carboxylic acid

Guidance literature:: In water; for 4h; Heating;
DOI:10.1007/BF00503484

Reference yield: 51.0%

: 1,5-naphthyridine-4-carbonitrile

: 79426-14-5
1,5-naphthyridine-4-carboxylic acid

Guidance literature:: With water; potassium hydroxide; In isopropyl alcohol; at 25 - 100 ℃; for 2h;

Reference yield:

: 7689-63-6
4-chloro-1,5-naphthyridine

: 79426-14-5
1,5-naphthyridine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 79.9 percent / 30percent H₂O₂ / Na₂WO₄*2H₂O / 96 h / 20 °C

2: 1. Na / 1. toluene, 95 deg C; 105 deg C, 3 h

3: 79.5 percent / Br₂ / CHCl₃ / 4 h / Heating

4: 88 percent / H₂O / 4 h / Heating

With dihydrogen peroxide; bromine; sodium; sodium tungstate; In chloroform; water;
DOI:10.1007/BF00503484