2-BENZYLPYRROLIDINE HYDROCHLORIDE

Base Information

• Chemical Name: 2-BENZYLPYRROLIDINE HYDROCHLORIDE
• CAS No.: 936225-47-7
• Molecular Formula: C₁₁H₁₅N*ClH
• Molecular Weight: 197.708
• Mol file: 936225-47-7.mol

Synonyms:2-BENZYLPYRROLIDINE HYDROCHLORIDE

Chemical Property of 2-BENZYLPYRROLIDINE HYDROCHLORIDE

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

2-(Phenylmethyl)-pyrrolidineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-BENZYLPYRROLIDINE HYDROCHLORIDE

There total 3 articles about 2-BENZYLPYRROLIDINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Lithium; (R)-2-benzyl-pyrrolidine-1-sulfonate (144889-06-5) → (R)-2-benzylpyrrolidine hydrochloride (144889-08-7,936225-47-7)

Guidance literature:

With hydrogenchloride; water; In ethanol; Yield given; Heating;

DOI:10.1016/S0040-4039(00)61082-1

Reference yield:

phenyllithium (591-51-5) → (R)-2-benzylpyrrolidine hydrochloride (144889-08-7,936225-47-7)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / Ambient temperature

2: 2N HCl, H₂O / ethanol / Heating

With hydrogenchloride; water; In tetrahydrofuran; ethanol;

DOI:10.1016/S0040-4039(00)61082-1

Reference yield:

phenyllithium (591-51-5) + (R)-tetrahydro-3H-pyrrolo[1,2-c][1,2,3]oxathiazole 1,1-dioxide (143577-46-2) → (R)-2-benzylpyrrolidine hydrochloride (144889-08-7,936225-47-7)

Guidance literature:

With hydrogenchloride; water; multistep reaction;

DOI:10.1016/S0040-4039(00)61082-1

upstream raw materials:

phenyllithium

(R)-tetrahydro-3H-pyrrolo[1,2-c][1,2,3]oxathiazole 1,1-dioxide

Lithium; (R)-2-benzyl-pyrrolidine-1-sulfonate

Refernces