2,7-Dichloroquinoline-3-carbonitrile

Base Information

Chemical Name:2,7-Dichloroquinoline-3-carbonitrile
CAS No.:158583-91-6
Molecular Formula:C10H4Cl2N2
Molecular Weight:223.061
Hs Code.:2933499090
DSSTox Substance ID:DTXSID80565460
Wikidata:Q82450574
Mol file:158583-91-6.mol

Synonyms:2,7-Dichloroquinoline-3-carbonitrile;158583-91-6;MFCD09787675;2,7-DICHLORO-3-QUINOLINECARBONITRILE;DTXSID80565460;AKOS015946041;AB51958;3-Quinolinecarbonitrile, 2,7-dichloro-;NS-02733;CS-0328630;AS-871/43475617

Suppliers and Price of 2,7-Dichloroquinoline-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,7-Dichloroquinoline-3-carbonitrile
50mg
$ 110.00

SynQuest Laboratories
2,7-Dichloroquinoline-3-carbonitrile
1 g
$ 400.00

American Custom Chemicals Corporation
2,7-DICHLOROQUINOLINE-3-CARBONITRILE 95.00%
5MG
$ 504.69

Total 5 raw suppliers

Chemical Property of 2,7-Dichloroquinoline-3-carbonitrile

Chemical Property:

Vapor Pressure:2.18E-06mmHg at 25°C
Boiling Point:393.1°C at 760 mmHg
PKA:-4.54±0.50(Predicted)
Flash Point:191.5°C
PSA：36.68000
Density:1.49g/cm³
LogP:3.41328
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:221.9751535
Heavy Atom Count:14
Complexity:260

Purity/Quality:

98%min ^*data from raw suppliers

2,7-Dichloroquinoline-3-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC2=NC(=C(C=C21)C#N)Cl)Cl

Technology Process of 2,7-Dichloroquinoline-3-carbonitrile

There total 4 articles about 2,7-Dichloroquinoline-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 2,7-Dichloro-quinoline-3-carbaldehyde oxime

: 158583-91-6
2,7-Dichloro-quinoline-3-carbonitrile

Guidance literature:: With acetic anhydride; for 3h; Heating;

Reference yield: 64.0%

: 73568-33-9
2,7-dichloro-quinoline-3-carbaldehyde

: 158583-91-6
2,7-Dichloro-quinoline-3-carbonitrile

Guidance literature:: With sodium azide; trichlorophosphate; for 6.33333h; Reflux;
DOI:10.1155/2021/2408006

Reference yield:

: 588-07-8
3-Chloroacetanilide

: 158583-91-6
2,7-Dichloro-quinoline-3-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate

2: hydroxylamine hydrochloride; ammonium hydroxide

With ammonium hydroxide; hydroxylamine hydrochloride; trichlorophosphate;
DOI:10.1016/j.bmcl.2018.05.045