2-N-(4-chlorophenyl)pyridine-2,3-diamine

Base Information

Chemical Name:2-N-(4-chlorophenyl)pyridine-2,3-diamine
CAS No.:42048-23-7
Molecular Formula:C₁₁H₁₀ClN₃
Molecular Weight:219.673
Hs Code.:
European Community (EC) Number:961-059-4
ChEMBL ID:CHEMBL2097959
DSSTox Substance ID:DTXSID801346043
Mol file:42048-23-7.mol

Synonyms:2-N-(4-chlorophenyl)pyridine-2,3-diamine;42048-23-7;N2-(4-chlorophenyl)pyridine-2,3-diamine;MMV676524;CHEMBL2097959;SCHEMBL11394107;BVPIXCUHSLXOOR-UHFFFAOYSA-N;TCMDC-142349;DTXSID801346043;GR135486X;AKOS009281422;PD061294;FT-0723369;EN300-108349;SR-05000022729;SR-05000022729-1;Z367657310

Suppliers and Price of 2-N-(4-chlorophenyl)pyridine-2,3-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-N-(4-chlorophenyl)pyridine-2,3-diamine

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:219.0563250
Heavy Atom Count:15
Complexity:192

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(N=C1)NC2=CC=C(C=C2)Cl)N

Technology Process of 2-N-(4-chlorophenyl)pyridine-2,3-diamine

There total 5 articles about 2-N-(4-chlorophenyl)pyridine-2,3-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 26820-72-4
N-(4-chlorophenyl)-3-nitro-2-pyridinamine

: 42048-23-7
N²-(4-chlorophenyl)pyridine-2,3-diamine

Guidance literature:: With tin(II) chloride dihdyrate; In methanol; for 2h; Reflux;
DOI:10.1016/j.bmc.2014.11.001

Reference yield:

: 5470-18-8,34515-82-7
2-Chloro-3-nitropyridine

: 42048-23-7
N²-(4-chlorophenyl)pyridine-2,3-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / 3 h / 160 - 170 °C

2: 64 percent / H₂ / Raney nickel / ethyl acetate / Ambient temperature

With hydrogen; nickel; In ethyl acetate;

Reference yield:

: 106-47-8
4-chloro-aniline

: 42048-23-7
N²-(4-chlorophenyl)pyridine-2,3-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 18 h / 100 °C

2: hydrogen / ethyl acetate / 6 h / 20 °C

With hydrogen; potassium carbonate; In ethyl acetate; N,N-dimethyl-formamide;