Methyl iMidazo[1,5-a]pyridine-7-carboxylate

Base Information

• Chemical Name: Methyl iMidazo[1,5-a]pyridine-7-carboxylate
• CAS No.: 1377829-50-9
• Molecular Formula: C9H8N2O2
• Molecular Weight: 176.175
• Hs Code.: 2933990090
• Mol file: 1377829-50-9.mol

Synonyms:Methyl iMidazo[1,5-a]pyridine-7-carboxylate;Imidazo[1,5-a]pyridine-7-carboxylic acid methyl ester

Chemical Property of Methyl iMidazo[1,5-a]pyridine-7-carboxylate

Chemical Property:

• PSA: 43.60000
• LogP: 1.12090

Purity/Quality:

98% ^*data from raw suppliers

Methylimidazo[1,5-a]pyridine-7-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl iMidazo[1,5-a]pyridine-7-carboxylate

There total 1 articles about Methyl iMidazo[1,5-a]pyridine-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Cyano-4-carbomethoxypyridine (94413-64-6) → methyl imidazo[1,5-a]pyridine-7-carboxylate (1377829-50-9)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogen / methanol / 0.5 h / 20 °C / 760.05 Torr

2: 2 h / 100 °C

3: trichlorophosphate / 1,2-dichloro-ethane / 1 h / 90 °C

With hydrogen; trichlorophosphate; In methanol; 1,2-dichloro-ethane;

Reference yield: 100.0%

methyl imidazo[1,5-a]pyridine-7-carboxylate (1377829-50-9) → 1H-imidazol(1,5-a)pyridine-7-carboxylic acid (588720-29-0)

Guidance literature:

With hydrogenchloride; water; for 3h; Heating / reflux;

upstream raw materials:

2-Cyano-4-carbomethoxypyridine

Downstream raw materials:

1H-imidazol(1,5-a)pyridine-7-carboxylic acid

Refernces