AKOS AU36-M422

Base Information

• Chemical Name: AKOS AU36-M422
• CAS No.: 25229-74-7
• Molecular Formula: C15H9IO2
• Molecular Weight: 348.14
• Mol file: 25229-74-7.mol

Synonyms:CHEMBRDG-BB 5663733;AKOS AU36-M422;3-(4-IODOPHENYL)-2H-CHROMEN-2-ONE;3-(4-iodophenyl)-2H-chromen-2-one(SALTDATA: FREE)

Chemical Property of AKOS AU36-M422

Chemical Property:

• Vapor Pressure: 1.59E-08mmHg at 25°C
• Boiling Point: 456.7°C at 760 mmHg
• Flash Point: 230°C
• PSA: 30.21000
• Density: 1.729g/cm³
• LogP: 4.06460

Purity/Quality:

99% ^*data from raw suppliers

3-(4-Iodophenyl)-2H-chromen-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of AKOS AU36-M422

There total 3 articles about AKOS AU36-M422 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

para-diiodobenzene (624-38-4,1032416-46-8) + coumarin (91-64-5) → 3-(4-iodophenyl)-2H-chromen-2-one (25229-74-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; silver(I) acetate; In N,N-dimethyl-formamide; at 80 ℃; for 72h; Inert atmosphere;

DOI:10.1055/s-0030-1259014

Reference yield:

→ 3-(4-iodophenyl)-2H-chromen-2-one (25229-74-7)

Guidance literature:

With pyridine hydrochloride;

Reference yield:

→ 3-(4-iodophenyl)-2H-chromen-2-one (25229-74-7)

Guidance literature:

Salicylaldehyd, 4-Iodphenylessigsaeure;

upstream raw materials:

para-diiodobenzene

coumarin

Downstream raw materials:

methyl (E)-3-[4-(coumarin-3-yl)phenyl]acrylate

Refernces