11-O-Galloylbergenin

Base Information

• Chemical Name: 11-O-Galloylbergenin
• CAS No.: 82958-44-9
• Molecular Formula: C21H20O13
• Molecular Weight: 480.382
• Mol file: 82958-44-9.mol

Synonyms:11-O-Galloylbergenin

Chemical Property of 11-O-Galloylbergenin

Chemical Property:

• Melting Point: 269℃
• Boiling Point: 887.5±65.0 °C(Predicted)
• PKA: 7.82±0.25(Predicted)
• PSA: 212.67000
• Density: 1.713±0.06 g/cm3(Predicted)
• LogP: -0.21910

Purity/Quality:

98%Min ^*data from raw suppliers

11-O-Galloylbergenin ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 11-O-Galloylbergenin

There total 2 articles about 11-O-Galloylbergenin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C35H32O13 (1350431-83-2) → 11-O-(3',4',5'-trihydroxygalloyl)bergenin (82958-44-9)

Guidance literature:

With palladium on carbon; hydrogen; In ethanol; dichloromethane;

DOI:10.1016/j.bmcl.2011.04.131

Reference yield:

bergenin (477-90-7) → 11-O-(3',4',5'-trihydroxygalloyl)bergenin (82958-44-9)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide; acetone

2: pyridine; dmap / dichloromethane / 0 - 20 °C

3: palladium on carbon; hydrogen / ethanol; dichloromethane

With pyridine; dmap; palladium on carbon; hydrogen; potassium carbonate; In ethanol; dichloromethane; N,N-dimethyl-formamide; acetone;

DOI:10.1016/j.bmcl.2011.04.131

Reference yield:

11-O-(3',4',5'-trihydroxygalloyl)bergenin (82958-44-9) → 3,4,5-trihydroxybenzoic acid (149-91-7) + bergenin (477-90-7)

Guidance literature:

With trifluoroacetic acid; In water; for 30h; Heating;

DOI:10.1016/S0031-9422(00)82451-6

upstream raw materials:

C₃₅H₃₂O₁₃

bergenin

Downstream raw materials:

3,4,5-trimethoxybenzoic acid methyl ester

3,4-dihydroxy-2-(hydroxymethyl)-8,9,10-trimethoxy-2,3,4,4a-tetrahydropyrano[3,2-c]isochromen6(10bH)-one

3,4,5-trihydroxybenzoic acid

bergenin