(alphaS)-alpha-Amino-1-methylcyclohexaneacetic acid

Base Information

• Chemical Name: (alphaS)-alpha-Amino-1-methylcyclohexaneacetic acid
• CAS No.: 455936-38-6
• Molecular Formula: C9H17NO2
• Molecular Weight: 171.23678
• Hs Code.: 2922498590
• Mol file: 455936-38-6.mol

Synonyms:(alphaS)-alpha-Amino-1-methylcyclohexaneacetic acid

Chemical Property of (alphaS)-alpha-Amino-1-methylcyclohexaneacetic acid

Chemical Property:

• Boiling Point: 291℃
• Flash Point: 130℃
• PSA: 63.32000
• Density: 1.078
• LogP: 2.06900

Purity/Quality:

99% ^*data from raw suppliers

Cyclohexaneaceticacid,.alpha.-amino-1-methyl-,(.alpha.S)- 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (alphaS)-alpha-Amino-1-methylcyclohexaneacetic acid

There total 9 articles about (alphaS)-alpha-Amino-1-methylcyclohexaneacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H25NO3 (951789-89-2) → C9H17NO2 (455936-38-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 16h;

DOI:10.1016/j.tetlet.2007.07.002

Reference yield:

C16H23NO → C9H17NO2 (455936-38-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: CHCl₃ / 16 h / 0 - 20 °C

2.1: HCl / methanol / 72 h / 0 - 20 °C

2.2: HCl / H₂O / 48 h / Heating

3.1: H₂ / Pd/C / methanol / 16 h / 20 °C

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; chloroform; 1.1: Strecker reaction;

DOI:10.1016/j.tetlet.2007.07.002

Reference yield:

C17H24N2O (951789-75-6) → C9H17NO2 (455936-38-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: HCl / methanol / 72 h / 0 - 20 °C

1.2: HCl / H₂O / 48 h / Heating

2.1: H₂ / Pd/C / methanol / 16 h / 20 °C

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1016/j.tetlet.2007.07.002

upstream raw materials:

C₁₇H₂₅NO₃

C₁₇H₂₄N₂O

C₁₇H₂₆N₂O₂

1-methyl-1-cyclohexanecarboxylic acid

Downstream raw materials:

(S)-2-(tert-butoxycarbonylamino)-2-(1-methylcyclohexyl)acetic acid

C₂₃H₃₈N₂O₅

C₂₂H₃₇N₃O₄

C₂₃H₃₉N₃O₄

Refernces