2-[4-(4-Methylbenzene-1-sulfonyl)-1H-imidazol-1-yl]pyridine

Base Information

Chemical Name:2-[4-(4-Methylbenzene-1-sulfonyl)-1H-imidazol-1-yl]pyridine
CAS No.:80781-10-8
Molecular Formula:C15H13N3O2S
Molecular Weight:299.34762
Hs Code.:
DSSTox Substance ID:DTXSID60697970
Wikidata:Q82628013
Mol file:80781-10-8.mol

Synonyms:DTXSID60697970;2-[4-(4-Methylbenzene-1-sulfonyl)-1H-imidazol-1-yl]pyridine

Suppliers and Price of 2-[4-(4-Methylbenzene-1-sulfonyl)-1H-imidazol-1-yl]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(4'-PYRIDINYL)-4-TOSYLIMIDAZOLE 95.00%
5MG
$ 503.25

Total 5 raw suppliers

Chemical Property of 2-[4-(4-Methylbenzene-1-sulfonyl)-1H-imidazol-1-yl]pyridine

Chemical Property:

Vapor Pressure:8.73E-12mmHg at 25°C
Boiling Point:554.9°C at 760 mmHg
Flash Point:289.4°C
PSA：73.23000
Density:1.31g/cm³
LogP:3.48930
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:299.07284784
Heavy Atom Count:21
Complexity:440

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

1-(4'-PYRIDINYL)-4-TOSYLIMIDAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)C2=CN(C=N2)C3=CC=CC=N3

Technology Process of 2-[4-(4-Methylbenzene-1-sulfonyl)-1H-imidazol-1-yl]pyridine

There total 3 articles about 2-[4-(4-Methylbenzene-1-sulfonyl)-1H-imidazol-1-yl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 38622-91-2,36635-61-7
[(p-methylphenyl)sulfonylmethyl]isonitrile

: 16705-92-3
4-<(ethoxymethylene)amino>pyridine

: 80781-10-8
4-(4-tosyl-1H-imidazol-1-yl)pyridine

Guidance literature:: With sodium hydride; In 1,2-dimethoxyethane; for 2h; Ambient temperature;
DOI:10.1021/jo00132a013

Reference yield: 45.0%

: 39910-67-3
4-azidopyridine

: 38622-91-2,36635-61-7
[(p-methylphenyl)sulfonylmethyl]isonitrile

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 80781-10-8
4-(4-tosyl-1H-imidazol-1-yl)pyridine

Guidance literature:: [(p-methylphenyl)sulfonylmethyl]isonitrile; N,N-dimethyl-formamide; With potassium tert-butylate; at 0 ℃; for 0.0333333h;

4-azidopyridine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.5h;
DOI:10.1021/acs.joc.9b02546

Reference yield:

: 504-24-5
4-aminopyridine

: 80781-10-8
4-(4-tosyl-1H-imidazol-1-yl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 55 percent / p-toluenesulfonic acid / 16 h / Heating

2: 90 percent / NaH / 1,2-dimethoxy-ethane / 2 h / Ambient temperature

With sodium hydride; toluene-4-sulfonic acid; In 1,2-dimethoxyethane;
DOI:10.1021/jo00132a013