Ethyl 5-amino-1-(2,6-difluorophenyl)-1H-pyrazole-3-carboxylate

Base Information

Chemical Name:Ethyl 5-amino-1-(2,6-difluorophenyl)-1H-pyrazole-3-carboxylate
CAS No.:1138036-69-7
Molecular Formula:C12H11F2N3O2
Molecular Weight:267.235
Hs Code.:
Mol file:1138036-69-7.mol

Synonyms:Ethyl 5-amino-1-(2,6-difluorophenyl)-1H-pyrazole-3-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl 5-amino-1-(2,6-difluorophenyl)-1H-pyrazole-3-carboxylate

Chemical Property:

PSA：70.14000
LogP:2.49060

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Technology Process of Ethyl 5-amino-1-(2,6-difluorophenyl)-1H-pyrazole-3-carboxylate

There total 1 articles about Ethyl 5-amino-1-(2,6-difluorophenyl)-1H-pyrazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 119452-66-3
(2,6-difluorophenyl)hydrazine

: potassium (Z)-1-cyano-3-ethoxy-3-oxoprop-1-en-2-olate

: 1138036-69-7
Ethyl 5-amino-1-(2,6-difluorophenyl)-1H-pyrazole-3-carboxylate

Guidance literature:: (2,6-difluorophenyl)hydrazine; potassium (Z)-1-cyano-3-ethoxy-3-oxoprop-1-en-2-olate; With sulfuric acid; In chloroform; water; at 20 ℃; for 18h;

With sodium hydrogencarbonate; In dichloromethane; chloroform; water;

With triethylamine; more than 3 stages;