(+/-)-1-AMINOCYCLOPENTANE-CIS-1,3-DICARBOXYLIC ACID

Base Information

Chemical Name:(+/-)-1-AMINOCYCLOPENTANE-CIS-1,3-DICARBOXYLIC ACID
CAS No.:39026-63-6
Molecular Formula:C₇H₁₁NO₄
Molecular Weight:173.169
Hs Code.:
Mol file:39026-63-6.mol

Synonyms:(+/-)-1-AMINOCYCLOPENTANE-CIS-1,3-DICARBOXYLIC ACID;(+/-)-1-AMINO-CIS-CYCLOPENTANE-1,3-DICARBOXYLIC ACID;1-AMINO-CIS-CYCLOPENTANE-1,3-DICARBOXYLIC ACID;(+/-)-CIS-1-AMINOCYCLOPENTANE-1,3-DICARBOXYLIC ACID;CIS-ACPD;(+/-)-1-AMINO-CIS-CYCLOPENTANE-1 3- &;(+/-)-1-aminocyclopentane-1,3-dicarboxylic acid

Suppliers and Price of (+/-)-1-AMINOCYCLOPENTANE-CIS-1,3-DICARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
cis-ACPD
10mg
$ 446.00

TRC
cis-ACPD
10mg
$ 90.00

Tocris
cis-ACPD
10
$ 154.00

Tocris
cis-ACPD
50
$ 632.00

Medical Isotopes, Inc.
(+-)-1-AMINOCYCLOPENTANE-cis-1,3-DICARBOXYLICACID
5 mg
$ 870.00

American Custom Chemicals Corporation
(+/-)-1-AMINOCYCLOPENTANE-CIS-1,3-DICARBOXYLIC ACID 95.00%
10MG
$ 436.80

AHH
1-Amino-cis-cyclopentane-1,3-dicarboxylicacid 98%
0.025g
$ 330.00

Total 21 raw suppliers

Chemical Property of (+/-)-1-AMINOCYCLOPENTANE-CIS-1,3-DICARBOXYLIC ACID

Chemical Property:

Vapor Pressure:6.39E-06mmHg at 25°C
Boiling Point:352.7°C at 760 mmHg
Flash Point:167.1°C
PSA：100.62000
Density:1.452g/cm³
LogP:0.35350
Storage Temp.:Store at RT
Solubility.:H2O: 1 mg/mL

Purity/Quality:

97% ^*data from raw suppliers

cis-ACPD ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Uses cis-ACPD was used in the study of activation of glutamate receptors in ischemic brain stem to determine enhanced release of taurine.It is a NMDA receptor agonist.

Technology Process of (+/-)-1-AMINOCYCLOPENTANE-CIS-1,3-DICARBOXYLIC ACID

There total 12 articles about (+/-)-1-AMINOCYCLOPENTANE-CIS-1,3-DICARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: (1S,3S)-1-tert-Butoxycarbonylamino-3-cyano-cyclopentanecarboxylic acid ethyl ester

: 39026-63-6,39026-64-7,56827-69-1,67684-64-4,89253-38-3,100910-67-6,111900-31-3,111900-32-4,111900-33-5,477331-06-9
trans-(+/-)-1-amino-1,3-cyclopentanedicarboxylic acid

Guidance literature:: With hydrogenchloride; ammonium hydroxide; Dowex 50WX₈-100; 1.) reflux, 4 h;
DOI:10.1016/S0040-4039(98)00490-0

Reference yield:

: 112896-82-9,112965-97-6,112965-98-7,112965-99-8,122743-40-2,122743-41-3
(5R,7S)-2,4-Dioxo-1,3-diaza-spiro[4.4]nonane-7-carboxylic acid

: 39026-63-6,39026-64-7,56827-69-1,67684-64-4,89253-38-3,100910-67-6,111900-31-3,111900-32-4,111900-33-5,477331-06-9
trans-1-aminocyclopentane-1,3-dicarboxylic acid

Guidance literature:: With barium(II) oxide; at 140 ℃;
DOI:10.1016/S0040-4039(00)82278-9

Reference yield:

: (1S,3S)-3-Acetoxy-1-tert-butoxycarbonylamino-cyclopentanecarboxylic acid ethyl ester

: 39026-63-6,39026-64-7,56827-69-1,67684-64-4,89253-38-3,100910-67-6,111900-31-3,111900-32-4,111900-33-5,477331-06-9
trans-1-aminocyclopentane-1,3-dicarboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 66 percent / K₂CO₃ / ethanol

2: Et₃N / CH₂Cl₂ / 17 h / 0 deg C up to RT

3: dimethylformamide / 17 h / 80 °C

4: 1.) 6M HCl; 2.) Dowex 50WX₈-100, 2M aq. NH₃ / 1.) reflux, 4 h

With hydrogenchloride; ammonium hydroxide; Dowex 50WX₈-100; potassium carbonate; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(98)00490-0