GM7W4YJ5XS

Base Information

• Chemical Name: GM7W4YJ5XS
• CAS No.: 865759-10-0
• Molecular Formula: C₂₅H₂₄N₆O₂
• Molecular Weight: 440.505
• UNII: GM7W4YJ5XS
• Mol file: 865759-10-0.mol

Synonyms:865759-10-0;GM7W4YJ5XS;SCHEMBL386747;KVIRZRAVCGZEMX-JOCHJYFZSA-N;(R)-2,2'-((6-(3-aminopiperidin-1-yl)-2,4-dioxopyrimidine-1, 3(2H,4H)-diyl)bis(methylene))dibenzonitrile;N-Desmethyl,N-2(2-cyanobenzyl) Alogliptin, (R)-;(R)-2,2'-((6-(3-aminopiperidin-1-yl)-2,4-dioxopyrimidine-1,3(2H,4H)-diyl)bis(methylene))dibenzonitrile;2,2'-[[6-[(3R)-3-Amino-1-piperidinyl]-2,4-dioxo-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[benzonitrile];2-{6-[3(R)-Amino-piperidin-1-yl]-3-(2-cyano-benzyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl}-benzonitrile;Benzonitrile, 2,2'-[[6-[(3R)-3-amino-1-piperidinyl]-2,4-dioxo-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis-

Chemical Property of GM7W4YJ5XS

Chemical Property:

• Boiling Point: 651.9±65.0 °C(Predicted)
• PKA: 9.89±0.20(Predicted)
• PSA: 120.84000
• Density: 1.37±0.1 g/cm3(Predicted)
• LogP: 2.54276
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 440.19607403
• Heavy Atom Count: 33
• Complexity: 882

Purity/Quality:

NLT 98% ^*data from raw suppliers

N-Desmethyl,N-2(2-cyanobenzyl)Alogliptin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC(CN(C1)C2=CC(=O)N(C(=O)N2CC3=CC=CC=C3C#N)CC4=CC=CC=C4C#N)N
• Isomeric SMILES: C1C[C@H](CN(C1)C2=CC(=O)N(C(=O)N2CC3=CC=CC=C3C#N)CC4=CC=CC=C4C#N)N
• Uses: N-Desmethyl,N-2(2-cyanobenzyl) Alogliptin is an impurity of Alogliptin (A575425), which is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4).Antidiabetic agent.

Technology Process of GM7W4YJ5XS

There total 1 articles about GM7W4YJ5XS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-{6-[3(R)-amino-piperidin-1-yl]-3-(2-cyano-benzyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl}-benzonitrile (865759-10-0)

Guidance literature: