5-tert-butyl-2,3-dihydro-1H-inden-1-amine

Base Information

Chemical Name:5-tert-butyl-2,3-dihydro-1H-inden-1-amine
CAS No.:935680-90-3
Molecular Formula:C₁₃H₁₉N
Molecular Weight:189.301
Hs Code.:
DSSTox Substance ID:DTXSID00467710
Mol file:935680-90-3.mol

Synonyms:935680-90-3;5-tert-butyl-2,3-dihydro-1H-inden-1-amine;5-TERT-BUTYL-1-AMINO-INDAN;5-(tert-Butyl)-2,3-dihydro-1H-inden-1-amine;5-tert-butyl-2,3-dihydro-1H-inden-1-ylamine;SCHEMBL1856329;1H-Inden-1-amine, 5-(1,1-dimethylethyl)-2,3-dihydro-;DTXSID00467710;JYRVCRJPCWMDQT-UHFFFAOYSA-N;MFCD11040621;AKOS006308599;P16660

Suppliers and Price of 5-tert-butyl-2,3-dihydro-1H-inden-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-TERT-BUTYL-2,3-DIHYDRO-1H-INDEN-1-AMINE 95.00%
5MG
$ 504.30

AccelPharmtech
5-tert-butyl-2,3-dihydro-1H-inden-1-amine 97.00%
25G
$ 6000.00

AccelPharmtech
5-tert-butyl-2,3-dihydro-1H-inden-1-amine 97.00%
5G
$ 3230.00

AccelPharmtech
5-tert-butyl-2,3-dihydro-1H-inden-1-amine 97.00%
1G
$ 1890.00

Total 6 raw suppliers

Chemical Property of 5-tert-butyl-2,3-dihydro-1H-inden-1-amine

Chemical Property:

Vapor Pressure:0.005mmHg at 25°C
Boiling Point:274.282°C at 760 mmHg
Flash Point:119.274°C
PSA：26.02000
Density:0.982g/cm³
LogP:3.63040
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:189.151749610
Heavy Atom Count:14
Complexity:204

Purity/Quality:

99% ^*data from raw suppliers

5-TERT-BUTYL-2,3-DIHYDRO-1H-INDEN-1-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC2=C(C=C1)C(CC2)N

Technology Process of 5-tert-butyl-2,3-dihydro-1H-inden-1-amine

There total 6 articles about 5-tert-butyl-2,3-dihydro-1H-inden-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 1056038-54-0
(Z)-5-tert-butyl-2,3-dihydro-1H-inden-1-one O-methyl oxime

: 935680-90-3
5-tert-butyl-2,3-dihydro-1H-inden-1-ylamine

Guidance literature:: With ammonia; hydrogen; palladium 10% on activated carbon; In methanol; for 6h; under 3102.97 Torr;

Reference yield:

: 935680-89-0
5-tert-butyl-1-indanone O-methyloxime

: 935680-90-3
5-tert-butyl-2,3-dihydro-1H-inden-1-ylamine

Guidance literature:: With ammonia; hydrogen; palladium on activated charcoal; In methanol; at 50 ℃; for 16h; under 3102.97 Torr;
DOI:10.1021/jm701007g

Reference yield:

: 253185-03-4,253185-04-5
tert-butylbenzene

: 935680-90-3
5-tert-butyl-2,3-dihydro-1H-inden-1-ylamine

Guidance literature:: Multi-step reaction with 5 steps

1.1: aluminum (III) chloride / dichloromethane / 0.25 h / 0 °C

1.2: 1.25 h / 0 °C

1.3: Cooling with ice

2.1: sulfuric acid / dichloromethane / 2 h / 90 °C

3.1: hydroxylamine hydrochloride; sodium acetate / methanol / 2 h / Reflux

4.1: potassium tert-butylate / tetrahydrofuran / 20 °C

4.2: 0 - 20 °C

5.1: hydrogen; ammonia / palladium 10% on activated carbon / methanol / 6 h / 3102.97 Torr

With aluminum (III) chloride; sulfuric acid; hydroxylamine hydrochloride; potassium tert-butylate; ammonia; hydrogen; sodium acetate; palladium 10% on activated carbon; In tetrahydrofuran; methanol; dichloromethane;