Ethyl 1-bromo-2,7-naphthyridine-3-carboxylate

Base Information

Chemical Name:Ethyl 1-bromo-2,7-naphthyridine-3-carboxylate
CAS No.:250674-54-5
Molecular Formula:C₁₁H₉BrN₂O₂
Molecular Weight:281.109
Hs Code.:2933990090
Mol file:250674-54-5.mol

Synonyms:Ethyl 1-bromo-2,7-naphthyridine-3-carboxylate;2,7-Naphthyridine-3-carboxylic acid, 1-broMo-, ethyl ester

Suppliers and Price of Ethyl 1-bromo-2,7-naphthyridine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl1-bromo-2,7-naphthyridine-3-carboxylate 95+%
1g
$ 880.00

Alichem
Ethyl1-bromo-2,7-naphthyridine-3-carboxylate
1g
$ 785.40

Total 5 raw suppliers

Chemical Property of Ethyl 1-bromo-2,7-naphthyridine-3-carboxylate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:433.922°C at 760 mmHg
PKA:1.25±0.30(Predicted)
Flash Point:216.229°C
PSA：52.08000
Density:1.557g/cm³
LogP:2.56900

Purity/Quality:

97% ^*data from raw suppliers

Ethyl1-bromo-2,7-naphthyridine-3-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ethyl 1-bromo-2,7-naphthyridine-3-carboxylate

There total 1 articles about Ethyl 1-bromo-2,7-naphthyridine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 38824-07-6
3-ethoxycarbonyl-2,7-naphthyridin-1-one

: 250674-54-5
1-bromo-[2,7]naphthyridine-3-carboxylic acid ethyl ester

Guidance literature:: With phosphorus(V) oxybromide;
DOI:10.1016/S0960-894X(99)00435-7

Reference yield:

: 250674-54-5
1-bromo-[2,7]naphthyridine-3-carboxylic acid ethyl ester

: [2,7]naphthyridine-3-carboxylic acid 2-methoxy-benzylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 42 percent / H₂; NaOAc / PdCl₂ / methanol / 2585.74 Torr

2: 78 percent / aq. LiOH / tetrahydrofuran

3: EDCI; HOBt / dimethylformamide

With lithium hydroxide; hydrogen; sodium acetate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium dichloride; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; 1: Catalytic hydrogenation / 2: Hydrolysis / 3: Acylation;
DOI:10.1016/S0960-894X(99)00435-7

Reference yield:

: 250674-54-5
1-bromo-[2,7]naphthyridine-3-carboxylic acid ethyl ester

: 250674-48-7
2,7-naphthyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 42 percent / H₂; NaOAc / PdCl₂ / methanol / 2585.74 Torr

2: 78 percent / aq. LiOH / tetrahydrofuran

With lithium hydroxide; hydrogen; sodium acetate; palladium dichloride; In tetrahydrofuran; methanol; 1: Catalytic hydrogenation / 2: Hydrolysis;
DOI:10.1016/S0960-894X(99)00435-7