3-Acetyl-5-broMo-2-hydroxybenzonitrile

Base Information

Chemical Name:3-Acetyl-5-broMo-2-hydroxybenzonitrile
CAS No.:1289080-94-9
Molecular Formula:C9H6BrNO2
Molecular Weight:240.056
Hs Code.:2926909090

Synonyms:3-Acetyl-5-broMo-2-hydroxybenzonitrile

Suppliers and Price of 3-Acetyl-5-broMo-2-hydroxybenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Acetyl-5-bromo-2-hydroxybenzonitrile 95+%
1g
$ 698.00

Alichem
3-Acetyl-5-bromo-2-hydroxybenzonitrile
1g
$ 579.36

Total 2 raw suppliers

Chemical Property of 3-Acetyl-5-broMo-2-hydroxybenzonitrile

Chemical Property:

PSA：61.09000
LogP:2.22898

Purity/Quality:

≥99% ^*data from raw suppliers

3-Acetyl-5-bromo-2-hydroxybenzonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Acetyl-5-broMo-2-hydroxybenzonitrile

There total 2 articles about 3-Acetyl-5-broMo-2-hydroxybenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

: 38873-07-3
acetic acid 4-bromo-2-cyanophenyl ester

: 1289080-94-9
3-acetyl-5-bromo-2-hydroxybenzonitrile

Guidance literature:: With aluminum (III) chloride; at 160 ℃; for 3h; Neat (no solvent);
DOI:10.1016/j.bmc.2011.01.047

Reference yield:

: 40530-18-5
5-bromo-2-hydroxybenzonitrile

: 1289080-94-9
3-acetyl-5-bromo-2-hydroxybenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 0.33 h

2: aluminum (III) chloride / 3 h / 160 °C / Neat (no solvent)

With aluminum (III) chloride; sulfuric acid; 2: Fries rearrangement;
DOI:10.1016/j.bmc.2011.01.047

Reference yield: 74.0%

: 1289080-94-9
3-acetyl-5-bromo-2-hydroxybenzonitrile

: 4659-47-6
2,3,6-trichlorobenzaldehyde

: 1289080-28-9
5-bromo-2-hydroxy-3-[3-(2,3,6-trichlorophenyl)-acryloyl]benzonitrile

Guidance literature:: 3-acetyl-5-bromo-2-hydroxybenzonitrile; 2,3,6-trichlorobenzaldehyde; With sodium hydroxide; In ethanol; water; at 20 ℃; for 6h;

With hydrogenchloride; In ethanol; water; pH=4;
DOI:10.1016/j.bmc.2011.01.047