1,3,4,5,6,7,8-heptafluoro-2-naphthaldehyde

Base Information

• Chemical Name: 1,3,4,5,6,7,8-heptafluoro-2-naphthaldehyde
• CAS No.: 52158-48-2
• Molecular Formula: C₁₁HF₇O
• Molecular Weight: 282.117
• Mol file: 52158-48-2.mol

Synonyms:1,3,4,5,6,7,8-heptafluoro-2-naphthaldehyde

Chemical Property of 1,3,4,5,6,7,8-heptafluoro-2-naphthaldehyde

Chemical Property:

• PSA: 17.07000
• LogP: 3.62600
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

1,3,4,5,6,7,8-Heptafluoro-2-naphthaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3,4,5,6,7,8-heptafluoro-2-naphthaldehyde

There total 8 articles about 1,3,4,5,6,7,8-heptafluoro-2-naphthaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

1,3,4,5,6,7,8-heptafluoro-2-naphthylmethyl methyl sulphoxide (137676-34-7) → 1,3,4,5,6,7,8-Heptafluoronaphthalene-2-carbaldehyde (52158-48-2) + 4,5,6,7,8,9-hexafluoronaphtho<1.2-c>-thiophene (137676-36-9) + 7-butyl-4,5,6,8,9-pentafluoronaphtho<1,2-c>thiophene (137676-38-1) + 8-butyl-4,5,6,7,9-pentafluoronaphtho<1,2-c>thiophene (137676-37-0)

Guidance literature:

With n-butyllithium; In hexane; at -70 ℃; for 4.5h;

Reference yield: 34.0%

octafluoronaphthalene (313-72-4) + dimsylsodium → 1,3,4,5,6,7,8-Heptafluoronaphthalene-2-carbaldehyde (52158-48-2) + 1,3,4,5,6,7,8-heptafluoro-2-naphthylmethyl methyl sulphoxide (137676-34-7)

Guidance literature:

In dimethyl sulfoxide; at -70 ℃; for 4h;

Reference yield: 11.0%

C14H7F7S2 → 1,3,4,5,6,7,8-Heptafluoronaphthalene-2-carbaldehyde (52158-48-2)

Guidance literature:

With 1,3,5-trichloro-2,4,6-triazine; dimethyl sulfoxide; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1002/anie.201711726

upstream raw materials:

octafluoronaphthalene

1,3,4,5,6,7,8-heptafluoro-2-naphthylmethyl methyl sulphoxide

2-Bromo-1,3,4,5,6,7,8-heptafluoronaphthalene

N-methyl-N-phenylformamide

Refernces

• 1、 Brooke, Gerald M.,Mawson, Simon D.. "Partially Fluorinated Heterocyclic Copmpounds. Part 27. The Synthesis of 4,5,6,7-Tetrafluorobenzothiophene and 4,5,6,7,8,9-Hexafluoronaphthothiophene; some Chemistry and Electrochemistry". . p. 1919 - 1923. Retrieved 2007/10/02.