2-(1H-indol-3-yl)-N-(2-nitrobenzyl)ethanamine

Base Information

Chemical Name:2-(1H-indol-3-yl)-N-(2-nitrobenzyl)ethanamine
CAS No.:355816-45-4
Molecular Formula:C17H17N3O2
Molecular Weight:295.341
Hs Code.:
DSSTox Substance ID:DTXSID00366032
Wikidata:Q82151084
ChEMBL ID:CHEMBL1620972
Mol file:355816-45-4.mol

Synonyms:2-(1H-indol-3-yl)-N-(2-nitrobenzyl)ethanamine;355816-45-4;CHEMBRDG-BB 5523128;[2-(1H-Indol-3-yl)-ethyl]-(2-nitro-benzyl)-amine;CBKinase1_000491;CBKinase1_012891;Cambridge id 5523128;CHEMBL1620972;SCHEMBL20797914;DTXSID00366032;STK145812;AKOS000546159;MLS-0347408.0002;BRD-K62434675-001-01-3;[2-(1H-INDOL-3-YL)ETHYL][(2-NITROPHENYL)METHYL]AMINE

Suppliers and Price of 2-(1H-indol-3-yl)-N-(2-nitrobenzyl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(1H-indol-3-yl)-N-(2-nitrobenzyl)ethanamine

Chemical Property:

Vapor Pressure:3.18E-10mmHg at 25°C
Boiling Point:502.4°C at 760 mmHg
Flash Point:257.7°C
Density:1.269g/cm³
XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:295.132076794
Heavy Atom Count:22
Complexity:371

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CNCCC2=CNC3=CC=CC=C32)[N+](=O)[O-]

Technology Process of 2-(1H-indol-3-yl)-N-(2-nitrobenzyl)ethanamine

There total 4 articles about 2-(1H-indol-3-yl)-N-(2-nitrobenzyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

: 61-54-1
tryptamine

: 552-89-6
2-nitro-benzaldehyde

: 355816-45-4
2-(1H-indol-3-yl)-N-(2-nitrobenzyl)ethanamine

Guidance literature:: With 2-picoline borane complex; acetic acid; In methanol; at 20 ℃; for 2h;
DOI:10.1016/j.ejmech.2019.01.012

Reference yield:

: 139655-02-0
C₁₇H₁₅N₃O₂

: 355816-45-4
2-(1H-indol-3-yl)-N-(2-nitrobenzyl)ethanamine

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1002/chem.201103207

Reference yield:

: 61-54-1
tryptamine

: 355816-45-4
2-(1H-indol-3-yl)-N-(2-nitrobenzyl)ethanamine

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 36 h / 20 °C / Inert atmosphere

2: sodium tetrahydroborate / methanol / 0 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; In methanol;
DOI:10.1002/chem.201103207