(2S,3S)-2,3-Diaminobutane-1,4-diol

Base Information

• Chemical Name: (2S,3S)-2,3-Diaminobutane-1,4-diol
• CAS No.: 151630-98-7
• Molecular Formula: C4H12N2O2
• Molecular Weight: 120.15
• DSSTox Substance ID: DTXSID00449218
• Nikkaji Number: J841.974D
• Wikidata: Q82268616
• Mol file: 151630-98-7.mol

Synonyms:(2S,3S)-2,3-DIAMINOBUTANE-1,4-DIOL;151630-98-7;DTXSID00449218;(2S,3S)-2,3-Diamino-1,4-butanediol

Chemical Property of (2S,3S)-2,3-Diaminobutane-1,4-diol

Chemical Property:

• PSA: 92.50000
• LogP: -0.97380
• XLogP3: -2.9
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 120.089877630
• Heavy Atom Count: 8
• Complexity: 52

Purity/Quality:

(2S,3S)-2,3-DIAMINOBUTANE-1,4-DIOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(CO)N)N)O
• Isomeric SMILES: C([C@H]([C@@H](CO)N)N)O

Technology Process of (2S,3S)-2,3-Diaminobutane-1,4-diol

There total 2 articles about (2S,3S)-2,3-Diaminobutane-1,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(2R,3R)-2,3-diazidobutane-1,4-diol (131063-52-0) → (2S,3S)-1,4-dihydroxy-2,3-diaminobutane (151630-98-7)

Guidance literature:

With hydrogen; platinum(IV) oxide; In methanol; water; for 24h; under 760 Torr; Ambient temperature;

DOI:10.1016/S0957-4166(97)00086-4

Reference yield: 93.0%

D-2,3-diazido-1,4-dibenzoylbutane (133268-20-9) → (2S,3S)-1,4-dihydroxy-2,3-diaminobutane (151630-98-7)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; for 48h;

DOI:10.1002/(sici)1099-0690(199909)1999:9<2033::aid-ejoc2033>3.0.co;2-k

Reference yield: 92.0%

2-Methoxybenzoyl chloride (21615-34-9) + (2S,3S)-1,4-dihydroxy-2,3-diaminobutane (151630-98-7) → C20H24N2O6 (1445949-44-9)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tet.2013.05.049

upstream raw materials:

(2R,3R)-2,3-diazidobutane-1,4-diol

D-2,3-diazido-1,4-dibenzoylbutane

Downstream raw materials:

C₂₀H₂₄N₂O₆