1-(3-Chlorophenyl)propan-2-amine

Base Information

Chemical Name:1-(3-Chlorophenyl)propan-2-amine
CAS No.:32560-59-1
Molecular Formula:C9H12ClN
Molecular Weight:169.654
Hs Code.:
UNII:8V8DE89CJE
ChEMBL ID:CHEMBL149022
DSSTox Substance ID:DTXSID501043400
Nikkaji Number:J565.897G
Mol file:32560-59-1.mol

Synonyms:1-(3-CHLOROPHENYL)PROPAN-2-AMINE;32560-59-1;3-Chloramphetamine;m-Chloroamphetamine;8V8DE89CJE;(+/-)-3-Chloroamphetamine;CHEMBL149022;2-(3-Chloro-phenyl)-1-methyl-ethylamine;Benzeneethanamine, 3-chloro-a-methyl-, (S)-;3-Chloroamphetamine;54676-34-5;Phenethylamine, m-chloro-.alpha.-methyl-;Benzeneethanamine, 3-chloro-.alpha.-methyl-;UNII-8V8DE89CJE;SCHEMBL266685;ORWQJKNRYUIFJU-UHFFFAOYSA-N;DTXSID501043400;1-(3-Chlorophenyl)-2-propanamine;BDBM50029103;MFCD08452661;MFCD20449144;MFCD20458062;3-Chloro-alpha-methylbenzeneethanamine;AKOS000152975;MB06208;Phenethylamine, m-chloro-alpha-methyl-;(R)-1-(3-Chlorophenyl)-2-propanamine;(S)-1-(3-Chlorophenyl)-2-propanamine;Benzeneethanamine, 3-chloro-alpha-methyl-;SY384296;SY384300;SY384301;NS00018425;EN300-58021;N11066;3-CHLORO-.ALPHA.-METHYLBENZENEETHANAMINE;AB01002132-01

Suppliers and Price of 1-(3-Chlorophenyl)propan-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(3-CHLOROPHENYL)PROPAN-2-AMINE 95.00%
1G
$ 676.71

Total 0 raw suppliers

Chemical Property of 1-(3-Chlorophenyl)propan-2-amine

Chemical Property:

Boiling Point:244.2±15.0 °C(Predicted)
PKA:9.70±0.10(Predicted)
PSA：26.02000
Density:1.096±0.06 g/cm3(Predicted)
LogP:2.93000
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:169.0658271
Heavy Atom Count:11
Complexity:116

Purity/Quality:: 1-(3-CHLOROPHENYL)PROPAN-2-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC(=CC=C1)Cl)N

Technology Process of 1-(3-Chlorophenyl)propan-2-amine

There total 5 articles about 1-(3-Chlorophenyl)propan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 19394-34-4
(E)-1-(3'-chlorophenyl)-2-nitropropene

: 32560-59-1
3-Chloro-Amphetamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane; for 18h; Inert atmosphere; Reflux;
DOI:10.1021/ml500113s

Reference yield: 11.0%

: 75-05-8,26809-02-9
acetonitrile

: 620-20-2,130468-19-8
1-Chloro-3-chloromethyl-benzene

: 32560-59-1
3-Chloro-Amphetamine

Guidance literature:: 1-Chloro-3-chloromethyl-benzene; With magnesium; In diethyl ether; Inert atmosphere;

acetonitrile; In diethyl ether; at 20 - 60 ℃; for 3h; Inert atmosphere;

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; at 0 ℃; for 3h; Inert atmosphere; Reflux;

Reference yield:

: 587-04-2
m-Chlorobenzaldehyde

: 32560-59-1
3-Chloro-Amphetamine

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium acetate / 7 h / Reflux; Inert atmosphere

2: lithium aluminium tetrahydride / dichloromethane; tetrahydrofuran / 18 h / Inert atmosphere; Reflux

With lithium aluminium tetrahydride; ammonium acetate; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ml500113s