Methyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoate

Base Information

Chemical Name:Methyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoate
CAS No.:781632-38-0
Molecular Formula:C17H13NO4
Molecular Weight:295.295
Hs Code.:2925190090
Mol file:781632-38-0.mol

Synonyms:Methyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoate

Suppliers and Price of Methyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Methyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoate 97%
1g
$ 524.00

Crysdot
Methyl3-((1,3-dioxoisoindolin-2-yl)methyl)benzoate 95+%
1g
$ 325.00

Chemenu
Methyl3-((1,3-dioxoisoindolin-2-yl)methyl)benzoate 95%
1g
$ 307.00

Atlantic Research Chemicals
Methyl3-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoate 95%
250mgs:
$ 116.64

AK Scientific
Methyl3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoate
1g
$ 757.00

Total 4 raw suppliers

Chemical Property of Methyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoate

Chemical Property:

PSA：63.68000
LogP:2.20730

Purity/Quality:

99%, ^*data from raw suppliers

Methyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Methyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoate

There total 3 articles about Methyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.5%

: 1074-82-4
potassium phtalimide

: 1129-28-8
3-methoxycarbonylbenzyl bromide

: 781632-38-0
3-(1, 3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-benzoic acid methyl ester

Guidance literature:: In N,N-dimethyl-formamide; at 85 ℃; for 12h;

Reference yield:

: 99-04-7
m-Toluic acid

: 781632-38-0
3-(1, 3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: N-Bromosuccinimide / 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 3 h / 25 °C / Reflux

2: thionyl chloride / 1 h / 25 °C / Reflux

3: N,N-dimethyl-formamide / 12 h / 85 °C

With N-Bromosuccinimide; thionyl chloride; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; N,N-dimethyl-formamide;

Reference yield:

: 6515-58-8
3-bromomethylbenzoic acid

: 781632-38-0
3-(1, 3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 1 h / 25 °C / Reflux

2: N,N-dimethyl-formamide / 12 h / 85 °C

With thionyl chloride; In N,N-dimethyl-formamide;