2-Chloro-6-methoxy-3-(2-nitroethenyl)quinoline

Base Information

Chemical Name:2-Chloro-6-methoxy-3-(2-nitroethenyl)quinoline
CAS No.:182050-23-3
Molecular Formula:C12H10ClN2O3
Molecular Weight:264.66
Hs Code.:
DSSTox Substance ID:DTXSID80694325
Mol file:182050-23-3.mol

Synonyms:182050-23-3;2-Chloro-6-methoxy-3-(2-nitroethenyl)quinoline;DTXSID80694325

Suppliers and Price of 2-Chloro-6-methoxy-3-(2-nitroethenyl)quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
E-2-CHLORO-6-METHOXY3-(2-NITRO)VINYLQUINOLINE 95.00%
5MG
$ 500.75

Total 2 raw suppliers

Chemical Property of 2-Chloro-6-methoxy-3-(2-nitroethenyl)quinoline

Chemical Property:

Vapor Pressure:2.89E-07mmHg at 25°C
Boiling Point:432°C at 760 mmHg
Flash Point:215.1°C
PSA：67.94000
Density:1.393g/cm³
LogP:3.66740
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:264.0301698
Heavy Atom Count:18
Complexity:332

Purity/Quality:

97% ^*data from raw suppliers

E-2-CHLORO-6-METHOXY3-(2-NITRO)VINYLQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=CC(=C(N=C2C=C1)Cl)C=C[N+](=O)[O-]

Technology Process of 2-Chloro-6-methoxy-3-(2-nitroethenyl)quinoline

There total 1 articles about 2-Chloro-6-methoxy-3-(2-nitroethenyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.9%

: 73568-29-3
2-chloro-6-methoxyquinolin-3-carboxaldehyde

: 75-52-5
nitromethane

: 182050-23-3
2-chloro-6-methoxy-3-(2-nitrovinyl)quinoline

Guidance literature:: With mesoporous nickel hydroxyapatite nanocomposite; for 0.0166667h; Microwave irradiation; Neat (no solvent);
DOI:10.1016/j.tetlet.2012.03.086

Reference yield: 77.0%

: N-benzyl-N-(methoxymethyl)trimethyl-silylamine

: 182050-23-3
2-chloro-6-methoxy-3-(2-nitrovinyl)quinoline

: 3-(1-benzyl-4-nitropyrrolidin-3-yl)-2-chloro-6-methoxyquinoline

Guidance literature:: N-benzyl-N-(methoxymethyl)trimethyl-silylamine; 2-chloro-6-methoxy-3-(2-nitrovinyl)quinoline; With trifluoroacetic acid; In acetonitrile; at 60 - 120 ℃; for 0.5 - 1.5h;

In acetonitrile;
DOI:10.3987/COM-10-S(E)77

Reference yield: 77.0%

: 182050-23-3
2-chloro-6-methoxy-3-(2-nitrovinyl)quinoline

: 93102-05-7
N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine

: 3-(1-benzyl-4-nitropyrrolidin-3-yl)-2-chloro-6-methoxyquinoline

Guidance literature:: 2-chloro-6-methoxy-3-(2-nitrovinyl)quinoline; N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine; With trifluoroacetic acid; In acetonitrile; Heating; Modular flow reactor;

With silica gel; In acetonitrile; Modular flow reactor;
DOI:10.1055/s-0029-1219344