YN968D1 Hydrochloride

Base Information

• Chemical Name: YN968D1 Hydrochloride
• CAS No.: 1218779-89-5
• Molecular Formula: C24H24ClN5O
• Molecular Weight: 433.93326
• Mol file: 1218779-89-5.mol

Synonyms:Apatinib Hydrochloride;N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylMethyl)aMino]-3-pyridinecarboxaMide;YN968D1 Hydrochloride

Chemical Property of YN968D1 Hydrochloride

Chemical Property:

• PSA: 149.31000
• LogP: 3.83260

Purity/Quality:

Safty Information:

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MSDS Files:

SDS file from LookChem

Useful:

• Uses: Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib enhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.

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