5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID ETHYL ESTER

Base Information

Chemical Name:5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID ETHYL ESTER
CAS No.:149210-23-1
Molecular Formula:C₁₃H₁₂N₂O₂S
Molecular Weight:260.316
Hs Code.:
Mol file:149210-23-1.mol

Synonyms:5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID ETHYL ESTER

Suppliers and Price of 5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID ETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID ETHYL ESTER

Chemical Property:

Melting Point:159 - 160 °C (CHCl3)
PSA：71.84000
LogP:3.03410

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID ETHYL ESTER

There total 2 articles about 5-METHYLIMIDAZO[2,1-B]BENZOTHIAZOLE-2-CARBOXYLIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 1477-42-5
4-methyl-1,3-benzothiazol-2-amine

: 70-23-5
ethyl Bromopyruvate

: 149210-23-1
ethyl 12-methyl-7-thia-2,5-diazatricyclo[6.4.0.0²^,⁶]dodeca-1⁽⁸⁾,3,5,9,11-pentaene-4-carboxylate

Guidance literature:: In 1,2-dimethoxyethane; for 6h; Heating;
DOI:10.1021/jm049680x

Reference yield: 45.0%

: 149210-23-1
ethyl 12-methyl-7-thia-2,5-diazatricyclo[6.4.0.0²^,⁶]dodeca-1⁽⁸⁾,3,5,9,11-pentaene-4-carboxylate

Guidance literature:

Reference yield:

: 149210-23-1
ethyl 12-methyl-7-thia-2,5-diazatricyclo[6.4.0.0²^,⁶]dodeca-1⁽⁸⁾,3,5,9,11-pentaene-4-carboxylate

: 623931-24-8
4-nitrobenzyl 6-[(acetyloxy)(5-methylimidazo[2,1-b][1,3]benzothiazol-2-yl)methyl]-6-bromo-7-oxo-4-thia-1-azabicylco[3.2.0]hept-2-ene-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 69 percent / LiAlH₄ / tetrahydrofuran / 1 h / 20 °C

2.1: 35 percent / MnO₂ / CHCl₃; methanol / 24 h / Heating

3.1: MgBr₂*Et₂O / tetrahydrofuran; acetonitrile / 0.5 h / 20 °C

3.2: Et₃N / tetrahydrofuran; acetonitrile / 16 h / -20 °C

3.3: 20 percent / tetrahydrofuran; acetonitrile / -20 - 0 °C

With manganese(IV) oxide; lithium aluminium tetrahydride; magnesium bromide; In tetrahydrofuran; methanol; chloroform; acetonitrile;
DOI:10.1021/jm049680x