2-Quinolinecarbonyl chloride, 8-hydroxy- (9CI)

Base Information

• Chemical Name: 2-Quinolinecarbonyl chloride, 8-hydroxy- (9CI)
• CAS No.: 125686-91-1
• Molecular Formula: C10H6ClNO2
• Molecular Weight: 207.61314
• Hs Code.: 2933499090
• Mol file: 125686-91-1.mol

Synonyms:2-Quinolinecarbonyl chloride, 8-hydroxy- (9CI)

Chemical Property of 2-Quinolinecarbonyl chloride, 8-hydroxy- (9CI)

Chemical Property:

• PSA: 50.19000
• LogP: 2.31940

Purity/Quality:

98%min ^*data from raw suppliers

8-Hydroxyquinoline-2-carbonyl chloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Quinolinecarbonyl chloride, 8-hydroxy- (9CI)

There total 1 articles about 2-Quinolinecarbonyl chloride, 8-hydroxy- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

8-hydroxy-quinoline-2-carboxylic acid (1571-30-8) → 8-hydroxyquinoline-2-carboxylic acid chloride (125686-91-1)

Guidance literature:

With oxalyl dichloride; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

DOI:10.1016/j.bmc.2008.09.052

Reference yield: 89.0%

8-hydroxyquinoline-2-carboxylic acid chloride (125686-91-1) + glycine benzyl ester p-toluenesulfonic acid salt (1738-76-7) → [(8-Hydroxy-quinoline-2-carbonyl)-amino]-acetic acid benzyl ester

Guidance literature:

With triethylamine; In benzene; for 20h; Ambient temperature;

DOI:10.1021/ja00162a038

Reference yield:

8-hydroxyquinoline-2-carboxylic acid chloride (125686-91-1) + sarcosine benzyl ester tosylate (54384-06-4) → [(8-Hydroxy-quinoline-2-carbonyl)-methyl-amino]-acetic acid benzyl ester

Guidance literature:

With triethylamine; In benzene; for 20h; Ambient temperature;

DOI:10.1021/ja00162a038

upstream raw materials:

8-hydroxy-quinoline-2-carboxylic acid

Downstream raw materials:

C₁₈H₁₆N₂O₃

C₁₇H₁₃ClN₂O₂

C₁₇H₁₄N₂O₃