1,4,5,6-Tetrahydro-1,2-dimethyl-6-(oxo)nicotinic acid ethyl ester

Base Information

Chemical Name:1,4,5,6-Tetrahydro-1,2-dimethyl-6-(oxo)nicotinic acid ethyl ester
CAS No.:10230-58-7
Molecular Formula:C₁₀H₁₅NO₃
Molecular Weight:197.234
Hs Code.:
Mol file:10230-58-7.mol

Synonyms:1,4,5,6-Tetrahydro-1,2-dimethyl-6-(oxo)nicotinic acid ethyl ester;1,4,5,6-Tetrahydro-1,2-dimethyl-6-oxo-3-pyridinecarboxylic acid ethyl ester

Suppliers and Price of 1,4,5,6-Tetrahydro-1,2-dimethyl-6-(oxo)nicotinic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1,4,5,6-Tetrahydro-1,2-dimethyl-6-(oxo)nicotinic acid ethyl ester

Chemical Property:

Boiling Point:190 - 195 °C (6 mmHg)
PSA：46.61000
LogP:1.01360

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,4,5,6-Tetrahydro-1,2-dimethyl-6-(oxo)nicotinic acid ethyl ester

There total 5 articles about 1,4,5,6-Tetrahydro-1,2-dimethyl-6-(oxo)nicotinic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: Ethyl 1,2-dimethyl-6-(2-nitrophenylimino)-1,4,5,6-tetrahydropyridine-3-carboxylate

: 10230-58-7
Ethyl 1,2-dimethyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 750.06 Torr; Ambient temperature;

Reference yield:

: 1721-26-2
ethyl 2-methyl nicotinate

: 10230-58-7
Ethyl 1,2-dimethyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 74 percent / ethyl acetate / 24 h / 40 °C

2: 73 percent / sodium dithionite, NaHCO₃ / H₂O; ethyl acetate / 1 h

3: 30 percent / benzene / 12 h / Ambient temperature

4: 30 percent / H₂ / 10percent Pd/C / ethanol / 750.06 Torr / Ambient temperature

With sodium dithionite; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In ethanol; water; ethyl acetate; benzene;

Reference yield:

: 10176-89-3
1,2-Dimethyl-3-ethoxycarbonylpyridinium iodide

: 10230-58-7
Ethyl 1,2-dimethyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / sodium dithionite, NaHCO₃ / H₂O; ethyl acetate / 1 h

2: 30 percent / benzene / 12 h / Ambient temperature

3: 30 percent / H₂ / 10percent Pd/C / ethanol / 750.06 Torr / Ambient temperature

With sodium dithionite; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In ethanol; water; ethyl acetate; benzene;