(13Z)-4-Hydroxy-2,11-dioxatricyclo[13.2.2.13,7]icosa-3,5,7(20),13,15,17(1),18-hepten-10-one

Base Information

Chemical Name:(13Z)-4-Hydroxy-2,11-dioxatricyclo[13.2.2.13,7]icosa-3,5,7(20),13,15,17(1),18-hepten-10-one
CAS No.:126191-23-9
Molecular Formula:C18H16 O4
Molecular Weight:296.32
Hs Code.:

Synonyms:2,11-Dioxatricyclo[13.2.2.13,7]eicosa-3,5,7(20),13,15,17,18-heptaen-10-one,4-hydroxy-, (Z)-; Combretastatin D2

Suppliers and Price of (13Z)-4-Hydroxy-2,11-dioxatricyclo[13.2.2.13,7]icosa-3,5,7(20),13,15,17(1),18-hepten-10-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
COMBRETASTATIN D2 95.00%
5MG
$ 499.88

Total 1 raw suppliers

Chemical Property of (13Z)-4-Hydroxy-2,11-dioxatricyclo[13.2.2.13,7]icosa-3,5,7(20),13,15,17(1),18-hepten-10-one

Chemical Property:

PSA：55.76000
Density:1.220
LogP:3.68710

Purity/Quality:: COMBRETASTATIN D2 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (13Z)-4-Hydroxy-2,11-dioxatricyclo[13.2.2.13,7]icosa-3,5,7(20),13,15,17(1),18-hepten-10-one

There total 55 articles about (13Z)-4-Hydroxy-2,11-dioxatricyclo[13.2.2.13,7]icosa-3,5,7(20),13,15,17(1),18-hepten-10-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 202645-47-4
(13R,14R)-4-hydroxy-13,14-dihydroxy-2,11-dioxatricyclo[13.2.2.1^3,7]eicosa-1⁽¹⁸⁾,3,5,7⁽²⁰⁾,1⁽¹⁹⁾,16-hexaen-10-one

: 126191-23-9
combretastatin D-2

Guidance literature:: With 1H-imidazole; tri-iodoimidazole; triphenylphosphine; In 1,1,2,2-tetrachloroethylene; at 140 ℃; for 0.5h;
DOI:10.1002/(SICI)1521-3765(199801)4:1<33::AID-CHEM33>3.0.CO;2-8

Reference yield: 67.0%

: 134209-01-1
combretastatin D₂ methyl ether

: 126191-23-9
combretastatin D-2

Guidance literature:: With aluminum (III) chloride; ethanethiol; In dichloromethane; at -17 ℃; for 1h;
DOI:10.1021/acs.joc.6b02586

Reference yield: 65.0%

: 202645-48-5
combretastatin D-2 benzyl ether

: 126191-23-9
combretastatin D-2

Guidance literature:: With aluminium trichloride; In dichloromethane; at 25 ℃; for 0.5h;
DOI:10.1002/(SICI)1521-3765(199801)4:1<33::AID-CHEM33>3.0.CO;2-8