(E)-tert-butyl 3-(4-((N-(3-((E)-3-methoxy-3-oxoprop-1-enyl)phenyl)cyclohexanecarboxamido)methyl)phenyl)acrylate

Base Information

Chemical Name:(E)-tert-butyl 3-(4-((N-(3-((E)-3-methoxy-3-oxoprop-1-enyl)phenyl)cyclohexanecarboxamido)methyl)phenyl)acrylate
CAS No.:592524-75-9
Molecular Formula:C31H37NO5
Molecular Weight:503.63
Hs Code.:
Mol file:592524-75-9.mol

Synonyms:(E)-tert-butyl 3-(4-((N-(3-((E)-3-methoxy-3-oxoprop-1-enyl)phenyl)cyclohexanecarboxamido)methyl)phenyl)acrylate

Suppliers and Price of (E)-tert-butyl 3-(4-((N-(3-((E)-3-methoxy-3-oxoprop-1-enyl)phenyl)cyclohexanecarboxamido)methyl)phenyl)acrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl3-(4-((N-(3-(3-methoxy-3-oxoprop-1-en-1-yl)phenyl)cyclohexanecarboxamido)methyl)phenyl)acrylate 97%
1g
$ 850.00

DC Chemicals
Fexaramate >98%
1 g
$ 2000.00

Crysdot
tert-Butyl3-(4-((N-(3-(3-methoxy-3-oxoprop-1-en-1-yl)phenyl)cyclohexanecarboxamido)methyl)phenyl)acrylate 97%
250mg
$ 340.00

Alichem
tert-Butyl3-(4-((N-(3-(3-methoxy-3-oxoprop-1-en-1-yl)phenyl)cyclohexanecarboxamido)methyl)phenyl)acrylate
1g
$ 858.50

Total 6 raw suppliers

Chemical Property of (E)-tert-butyl 3-(4-((N-(3-((E)-3-methoxy-3-oxoprop-1-enyl)phenyl)cyclohexanecarboxamido)methyl)phenyl)acrylate

Chemical Property:

PSA：72.91000
LogP:6.34120

Purity/Quality:

99%, ^*data from raw suppliers

tert-Butyl3-(4-((N-(3-(3-methoxy-3-oxoprop-1-en-1-yl)phenyl)cyclohexanecarboxamido)methyl)phenyl)acrylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-tert-butyl 3-(4-((N-(3-((E)-3-methoxy-3-oxoprop-1-enyl)phenyl)cyclohexanecarboxamido)methyl)phenyl)acrylate

There total 13 articles about (E)-tert-butyl 3-(4-((N-(3-((E)-3-methoxy-3-oxoprop-1-enyl)phenyl)cyclohexanecarboxamido)methyl)phenyl)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1663-39-4,25232-27-3
tert-Butyl acrylate

: (E)-methyl 3-(3-(N-(4-bromobenzyl)cyclohexanecarboxamido)phenyl)acrylate

: 592524-75-9
fexaramate

Guidance literature:: With triethylamine; tris-(o-tolyl)phosphine; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In N,N-dimethyl-formamide; at 90 ℃; for 12h;
DOI:10.1039/b300525a

Reference yield:

: 1055899-24-5
3-(4-{[(3-bromo-phenyl)-cyclohexanecarbonyl-amino]-methyl}-phenyl)-acrylic acid tert-butyl ester

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 592524-75-9
fexaramate

Guidance literature:: With triethylamine; tris-(o-tolyl)phosphine; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In N,N-dimethyl-formamide; at 90 ℃; for 12h;
DOI:10.1039/b300525a

Reference yield:

: 1663-39-4,25232-27-3
tert-Butyl acrylate

: 592524-75-9
fexaramate

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / Et₃N; P(o-tol)3 / Pd₂(dba)3 / dimethylformamide / 12 h / 90 °C

2: AcOH / methanol / 0.5 h / 25 °C

3: NaCNBH₃ / 1 h / 25 °C

4: Et₃N; 4-DMAP / CH₂Cl₂ / 1 h / 25 °C

With dmap; sodium cyanoborohydride; acetic acid; triethylamine; tris-(o-tolyl)phosphine; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In methanol; dichloromethane; N,N-dimethyl-formamide; 1: Heck coupling;
DOI:10.1039/b300525a