(±)-2-Bromooctane

Base Information

• Chemical Name: (±)-2-Bromooctane
• CAS No.: 60251-57-2
• Molecular Formula: C₈H₁₇Br
• Molecular Weight: 193.127
• Mol file: 60251-57-2.mol

Synonyms:Einecs 209-171-8;Nsc 8060;sec-Octyl bromide (van)

Chemical Property of (±)-2-Bromooctane

Chemical Property:

• Melting Point: -55°C (estimate)
• Refractive Index: 1.4442
• Boiling Point: 188.55°C
• PSA: 0.00000
• Density: 1.0878
• LogP: 3.74020

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (±)-2-Bromooctane

There total 30 articles about (±)-2-Bromooctane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

rac-octan-2-ol (4128-31-8,113301-48-7,4128-32-9) → 2-bromooctane (557-35-7,60251-57-2)

Guidance literature:

With carbon tetrabromide; tris[4-(2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctyloxy)phenyl]phosphane; In toluene; at 50 ℃; for 4h;

DOI:10.1016/j.tetlet.2003.08.064

Reference yield: 96.0%

2-Octyl tosylate (1028-12-2) → 2-bromooctane (557-35-7,60251-57-2)

Guidance literature:

With sodium bromide; In N,N-dimethyl-formamide; at 25 ℃; for 84h;

DOI:10.1139/v82-220

Reference yield: 96.0%

2-(2-tetrahydropyranyloxy)octane (140387-66-2,140387-67-3,69993-79-9,70702-57-7) → 2-bromooctane (557-35-7,60251-57-2)

Guidance literature:

With 1,2-bis (triphenylphosphino)ethane tetrabromide; In dichloromethane; at 23 ℃; for 4h;

DOI:10.1016/S0040-4039(01)80984-9

upstream raw materials:

rac-octan-2-ol

1,2-dibromooctane

p-toluenesulfonyl chloride

2-(2-tetrahydropyranyloxy)octane

Downstream raw materials:

hexyl-methyl-ketone

(1-methylheptyl)thiobenzene

octane

octane-2-thiol

Refernces

• 1、 -. "Construction of chiral liquid crystal phosphorescent material based on cyclometalated platinum complex and application of chiral liquid crystal phosphorescent material in circular polarizer". Paragraph 0021. . Retrieved 2020/06/09.
• 2、 Sargent, Brendon T.,Alexanian, Erik J.. "Palladium-Catalyzed Alkoxycarbonylation of Unactivated Secondary Alkyl Bromides at Low Pressure". supporting information. p. 7520 - 7523. Retrieved 2016/07/06.